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Mouse Models of Vascular Diseases

  • Book
  • © 2016

Overview

Editors:
  1. Masataka Sata

    1. Tokushima University, Tokushima, Japan

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  • Illustrates the entire process of establishing original mice models

  • Covers a wide range of vascular diseases

  • Provides readers with a strong tool for basic research on cardiovascular diseases and metabolic disorders

  • Includes supplementary material: sn.pub/extras

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-viii
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  2. Re-stenosis Models After Angioplasty

    1. Front Matter

      Pages 1-1
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    2. Wire-Mediated Endovascular Injury that Induces Rapid Onset of Medial Cell Apoptosis Followed by Reproducible Neointimal Hyperplasia

      • Masataka Sata, Kimie Tanaka, Daiju Fukuda
      Pages 3-20

    3. Cuff-Induced Neointimal Formation in Mouse Models

      • Tetsuya Kubota, Naoto Kubota
      Pages 21-41

    4. Ligation of the Mouse Common Carotid Artery

      • Sarah M. Peterson, Lucy Liaw, Volkhard Lindner
      Pages 43-68

    5. Photochemically Induced Endothelial Injury

      • Yuji Matsumoto, Kazuo Umemura
      Pages 69-86

  3. Thrombosis and Hemostasis Models

    1. Front Matter

      Pages 87-87
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    2. Murine Models of Thrombosis and Hemostasis

      • Brian C. Cooley
      Pages 89-109

  4. Transplant-Associated Atherosclerosis

    1. Front Matter

      Pages 111-111
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    2. Murine Heart Transplantation and Graft Arterial Disease

      • Jun-ichi Suzuki, Masahito Ogawa, Mitsuaki Isobe
      Pages 113-141

    3. Murine Models of Vein Grafting

      • Brian C. Cooley
      Pages 143-155

  5. Hyperlipidemia-Induced Atherosclerosis

    1. Front Matter

      Pages 157-157
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    2. Mouse Models of Atherosclerosis

      • Hiroshi Iwata, Jun-ichiro Koga, Julius Decano, Jung Choi, Andrew K. Mlynarchik, Peter C. Mattson et al.
      Pages 159-193

  6. Aneurysm in the Aorta

    1. Front Matter

      Pages 195-195
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    2. Angiotensin II-Induced Aortic Aneurysms in Mice

      • Hong Lu, Deborah A. Howatt, Anju Balakrishnan, Jessica J. Moorleghen, Debra L. Rateri, Lisa A. Cassis et al.
      Pages 197-210

    3. Mouse Model of Abdominal Aortic Aneurysm Induced by CaCl2

      • Hiroki Aoki, Satoko Ohno, Aya Furusho, Michihide Nishihara, Norifumi Nishida, Saki Hirakata et al.
      Pages 211-225

    4. Mouse Models of Aortic Aneurysm

      • Miyuki Kanematsu, Yasuhisa Kanematsu, Tomoki Hashimoto
      Pages 227-232

  7. Intracranial Aneurysm Models

    1. Front Matter

      Pages 233-233
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    2. Technical Aspects of Mouse Intracranial Aneurysm Model

      • Yoshiteru Tada, Masaaki Korai, Tomoki Hashimoto
      Pages 235-241

    3. Experimental Model of Cerebral Aneurysms in Ovariectomized Rats

      • Shinji Nagahiro, Keiko Kitazato
      Pages 243-259
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Keywords

About this book

This book is a methodological source on mice models of vascular diseases. Covering various areas, each chapter is written by a pioneering researcher who has developed an original vascular disease model. Notoriously difficult to reproduce, each model is described in detail and numerous photographs are provided with links to videos. Genetically modified mice are a very powerful tool for studying the pathogenesis of various diseases, including immunological and oncological disorders, but they had always been thought to be too small to be used in the field of cardiovascular disease. Recently, however, various mice models of vascular diseases have been reported, and these will make a substantial contribution to basic research on cardiovascular and metabolic disorders.    

Editors and Affiliations

  • Tokushima University, Tokushima, Japan

    Masataka Sata

About the editor

Masataka Sata, MD, PhD: Institute of Biomedical Sciences, Department of Cardiovascular Medicine, Tokushima University.

Bibliographic Information

  • Book Title: Mouse Models of Vascular Diseases

  • Editors: Masataka Sata

  • DOI: https://doi.org/10.1007/978-4-431-55813-2

  • Publisher: Springer Tokyo

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Japan 2016

  • Hardcover ISBN: 978-4-431-55811-8Published: 04 March 2016

  • Softcover ISBN: 978-4-431-56699-1Published: 07 April 2018

  • eBook ISBN: 978-4-431-55813-2Published: 19 February 2016

  • Edition Number: 1

  • Number of Pages: VIII, 296

  • Number of Illustrations: 28 b/w illustrations, 63 illustrations in colour

  • Topics: Cardiology, Metabolic Diseases, Animal Models

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