Overview
- Is a comprehensive, high-level clinical reference on the pathogenesis and therapy of hematological malignancies
- Provides the clinical experience of TKIs such as imatinib, nilotinib, dasatinib, and ponatinib
- Offers practical guidance on the therapeutic implications for understanding and managing CML
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Table of contents (12 chapters)
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Front Matter
Keywords
About this book
Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development. Included are therapeutic implications, diagnosis, and prognosis for understanding and facilitating daily practice in the management of patients with CML.
Understanding of the pathogenesis and therapy of hematological malignancies such as CML has grown significantly in recent years. This development owe much to the progress in molecular biology and now makes a major contribution to diagnosis and to treatment that pharmacologically targets the molecular events of CML. Molecular targeting therapy with newly developed agents such as small molecules and antibodies for hematological malignancies are being discovered after years of research. Some of these, including tyrosine kinase inhibitors such as imatinib, nilotinib, and dasatinib, lead to increased survival rates and improved therapies. With the opinion leaders of basic and clinical research in the field as authors, this book reviews recent advances in the biology of CML.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia
Editors: Masahiro Kizaki
DOI: https://doi.org/10.1007/978-4-431-55714-2
Publisher: Springer Tokyo
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Japan 2016
Hardcover ISBN: 978-4-431-55713-5Published: 13 November 2015
Softcover ISBN: 978-4-431-56255-9Published: 23 August 2016
eBook ISBN: 978-4-431-55714-2Published: 05 November 2015
Edition Number: 1
Number of Pages: VIII, 193
Number of Illustrations: 6 b/w illustrations, 20 illustrations in colour
Topics: Hematology, Oncology