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  • © 2016

Gene Therapy and Cell Therapy Through the Liver

Current Aspects and Future Prospects

  • Provides extensive information for examining the wide varieties of pathological conditions both inside and outside the liver

  • Focuses on cell therapy, gene therapy, and legal regulation of the application of therapies in different parts of the globe

  • Is especially relevant for principal investigators, researchers, postdocs and clinicians regarding current aspects and future prospects

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-x
  2. Liver-Targeted Gene and Cell Therapies: An Overview

    • Mohammad Alsaggar, Dexi Liu
    Pages 1-11
  3. Cell Therapy

    1. Front Matter

      Pages 13-13
    2. Macrophage Therapy for Liver Fibrosis and Regeneration

      • Atsunori Tsuchiya, Stuart J. Forbes
      Pages 15-23
    3. Cell-Based Immunotherapy for HCC: Our Experiences and Future Directions

      • Noriho Iida, Eishiro Mizukoshi, Shuichi Kaneko
      Pages 47-55
  4. Gene Therapy

    1. Front Matter

      Pages 57-57
    2. AAV Vector-Mediated Liver Gene Therapy and Its Implementation for Hemophilia

      • Hiroaki Mizukami, Jun Mimuro, Tsukasa Ohmori, Yoichi Sakata, Keiya Ozawa
      Pages 59-73
    3. Potential Usage of Human Artificial Chromosome for Regenerative Medicine

      • Narumi Uno, Yasuhiro Kazuki, Mitsuo Oshimura
      Pages 75-83
    4. Image-Guided Hydrodynamic Gene Delivery to the Liver: Toward Clinical Applications

      • Kenya Kamimura, Takeshi Suda, Tsutomu Kanefuji, Takeshi Yokoo, Hiroyuki Abe, Yuji Kobayashi et al.
      Pages 85-92
  5. Legal Regulation

    1. Front Matter

      Pages 93-93
    2. Regulation for Gene and Cell Therapy Medicinal Products in Europe

      • Matthias Renner, Brigitte Anliker, Egbert Flory, Jürgen Scherer, Martina Schüßler-Lenz, Matthias Schweizer et al.
      Pages 105-123
    3. iPSC-Derived Products: Current Regulations

      • Susan Solomon, Mahendra S. Rao
      Pages 125-137
    4. Critical Path Initiative for Regenerative Medicine in Japan

      • Hanayuki Okura, Akifumi Matsuyama
      Pages 139-146
  6. Industrialization

    1. Front Matter

      Pages 147-147

About this book

This book reports the recent progress in gene and cell therapy through the liver and aims to facilitate a comprehensive understanding of the current aspects and future prospects from basic research to clinical therapies. Edited by pioneering researchers, this volume presents extensive information to principal investigators, researchers, postdocs and clinicians for examining the wide varieties of pathological conditions both inside and outside the liver.

Providing not only the basic and clinical aspects of therapy, this volume is special in that it focuses on the administrative and regulatory difficulties of actual clinical application and legal regulations in different parts of the globe. By indicating the advantages and limitations of the most promising gene and cell therapies targeting the liver, this book will inspire readers to develop a feasible treatment in the next generation.

Editors and Affiliations

  • Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University , Niigata, Japan

    Shuji Terai

  • Department of Gastroenterology and Hepatology, Uonuma Institute of Community Medicine, Niigata University, Niigata, Japan

    Takeshi Suda

Bibliographic Information

  • Book Title: Gene Therapy and Cell Therapy Through the Liver

  • Book Subtitle: Current Aspects and Future Prospects

  • Editors: Shuji Terai, Takeshi Suda

  • DOI: https://doi.org/10.1007/978-4-431-55666-4

  • Publisher: Springer Tokyo

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Japan 2016

  • Hardcover ISBN: 978-4-431-55665-7Published: 27 October 2015

  • Softcover ISBN: 978-4-431-56251-1Published: 23 August 2016

  • eBook ISBN: 978-4-431-55666-4Published: 16 October 2015

  • Edition Number: 1

  • Number of Pages: X, 185

  • Topics: Hepatology, Gene Therapy, Gastroenterology, Regenerative Medicine/Tissue Engineering, Internal Medicine

Buy it now

Buying options

eBook USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access