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Idiopathic Pulmonary Fibrosis

Advances in Diagnostic Tools and Disease Management

  • Book
  • © 2016

Overview

Editors:
  1. Hiroyuki Nakamura

    1. Department of Respiratory Medicine, Tokyo Medical University, Ibaraki Medical Center , Ibaraki, Japan

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  2. Kazutetsu Aoshiba

    1. Department of Respiratory Medicine , Tokyo Medical University, Ibaraki Medical Center, Ibaraki, Japan

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Introducing new developments such as serum makers that are highly specific to IPF, the establishment of systematic diagnosis imaging and antifibrotic agent

  • Each chapter addresses key issues under discussion and provides perspective on future developments in the field

  • Valuable source for beginning learners to physicians, instructors and researchers whose work involves IIPs

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-x
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  2. Definition, Epidemiology, and Pathogenesis

    1. Front Matter

      Pages 1-1
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    2. Definition of IPF

      • Shinji Abe, Akihiko Gemma
      Pages 3-9

    3. Epidemiology and Risk Factors of IPF

      • Kazuyoshi Kuwano, Jun Araya, Hiromichi Hara
      Pages 11-25

    4. Acute Exacerbation of IPF

      • Yoshiki Ishii
      Pages 27-42

    5. Pathogenesis of IPF

      • Yasuhiko Nishioka
      Pages 43-58

  3. Diagnosis

    1. Front Matter

      Pages 59-59
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    2. Specific Serum Markers of IPF

      • Hirofumi Chiba, Hiroki Takahashi
      Pages 61-76

    3. High-Resolution Computed Tomography of Honeycombing and IPF/UIP

      • Fumikazu Sakai
      Pages 77-104

    4. Pathology of IPF

      • Yoshinori Kawabata
      Pages 105-132

    5. Differential Diagnosis of IPF

      • Hidehiro Watanabe
      Pages 133-144

  4. Management and Prognosis

    1. Front Matter

      Pages 145-145
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    2. Pharmacotherapy of IPF Using Antifibrotic Compounds

      • Tomohiro Handa, Arata Azuma
      Pages 147-159

    3. Pharmacotherapy of IPF (Corticosteroids, Immunosuppressants, Etc.)

      • Masashi Bando
      Pages 161-170

    4. Non-pharmacological Therapy for IPF

      • Yukihiro Umeda, Tamotsu Ishizuka, Takeshi Ishizaki
      Pages 171-188

    5. Pharmacotherapy of Acute Exacerbation of IPF (Corticosteroids, Immunosuppressants, and Direct Hemoperfusion with Polymyxin)

      • Masayuki Itoh
      Pages 189-201

  5. Topics

    1. Front Matter

      Pages 203-203
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    2. Combined Pulmonary Fibrosis and Emphysema (CPFE)

      • Yoshiteru Morio, Kazuhisa Takahashi
      Pages 205-215

    3. Common Pathways in IPF and Lung Cancer

      • Nobuyuki Koyama
      Pages 217-247

    4. Acute Exacerbation of Interstitial Pneumonia After Pulmonary Resection for Lung Cancer

      • Hiroshi Date
      Pages 249-259
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Keywords

About this book

From epidemiology and pathogenesis to disease management, this book reviews our current understanding of and provides up-to-date information of Idiopathic Pulmonary Fibrosis (IPF). A subtype of Idiopathic Interstitial Pneumonias (IIP), IPF is one of the most elusive and intractable respiratory disease to date and its triggering factors remain unclear. However, new developments such as serum markers that are highly specific to IPF (i.e. KL-6, SP-A, and SP-D), the establishment of systematic diagnostic imaging (HRCT) and accumulated reports of treatment using an antifibrotic agent (pirfenidone) are slowly improving our understanding of the disease. Edited by an established authority in the field and written by experts, this book will be valuable to not only to beginning learners but also to physicians, instructors and researchers whose work involves IIPs. With each chapter exploring critical questions, with unresolved issues and future prospects, the book offers a valuable resource for understanding issues such as the newly proposed entity of interstitial pneumonia with emphysema (combined pulmonary fibrosis and emphysema: CPFE) and the mechanism of how so many IIP sufferers develop lung cancer.

Editors and Affiliations

  • Department of Respiratory Medicine, Tokyo Medical University, Ibaraki Medical Center , Ibaraki, Japan

    Hiroyuki Nakamura

  • Department of Respiratory Medicine , Tokyo Medical University, Ibaraki Medical Center, Ibaraki, Japan

    Kazutetsu Aoshiba

About the editors

Hiroyuki Nakamura, MD, PhD.

Department of Respiratory Medicine,

Tokyo Medical University Ibaraki Medical Center, Japan

Kazutetsu Aoshiba, MD, PhD.

Department of Respiratory Medicine,

Tokyo Medical University Ibaraki Medical Center, Japan

Bibliographic Information

  • Book Title: Idiopathic Pulmonary Fibrosis

  • Book Subtitle: Advances in Diagnostic Tools and Disease Management

  • Editors: Hiroyuki Nakamura, Kazutetsu Aoshiba

  • DOI: https://doi.org/10.1007/978-4-431-55582-7

  • Publisher: Springer Tokyo

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Japan 2016

  • Hardcover ISBN: 978-4-431-55581-0Published: 08 October 2015

  • Softcover ISBN: 978-4-431-56281-8Published: 23 August 2016

  • eBook ISBN: 978-4-431-55582-7Published: 28 September 2015

  • Edition Number: 1

  • Number of Pages: X, 259

  • Topics: Pneumology/Respiratory System, Cytokines and Growth Factors

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