Basics of Flow Microreactor Synthesis

1. Front Matter

   Pages i-ix

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2. Departure from Flask Chemistry

   • Jun-ichi Yoshida

   Pages 1-8

3. Controlling Residence Time

   • Jun-ichi Yoshida

   Pages 9-19

4. Fast Micromixing for High-Resolution Reaction Time Control

   • Jun-ichi Yoshida

   Pages 21-30

5. Use of Short-Lived Reactive Species Achieved by High-Resolution Reaction Time Control

   • Jun-ichi Yoshida

   Pages 31-41

6. Protecting-Group-Free Synthesis Achieved by High-Resolution Reaction Time Control

   • Jun-ichi Yoshida

   Pages 43-50

7. Controlling Isomerization by High-Resolution Reaction Time Control

   • Jun-ichi Yoshida

   Pages 51-58

8. Controlling Competitive Consecutive Reactions Using Micromixing

   • Jun-ichi Yoshida

   Pages 59-71

9. Flash Chemistry

   • Jun-ichi Yoshida

   Pages 73-77

10. Space Integration of Reactions

    • Jun-ichi Yoshida

    Pages 79-86

11. Polymerization Using Flow Microreactor System

    • Jun-ichi Yoshida

    Pages 87-99

12. Outlook

    • Jun-ichi Yoshida

    Pages 101-101

13. Back Matter

    Pages 103-108

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This book provides in a concise form the principles and applications of flow microreactors in organic and polymer synthesis. Recently, it became possible to conduct chemical reactions in a flow reactor in laboratory synthesis. The flow microreactor enables reactions that cannot be done in batch, opening a new possibility of chemical synthesis. Extremely fast mass and heat transfer and high-resolution residence time control are responsible for the remarkable features of that process. The book is not an exhaustive compilation of all known examples of flow microreactor synthesis. Rather, it is a sampling of sufficient variety to illustrate the concept, the scope, and the current state of flow microreactor synthesis. Researchers both in academia and in industry will be interested in this book because the topics encompassed by the book are vigorously studied in many university and company laboratories today.

• Flash Chemistry
• Flow Chemistry
• Flow Microreactor
• Micromixing
• Residence Time Control

“This monograph gives a nice introduction to the field of flow chemistry and represents definitely a must-have for most people that are new in the field. … the book is of great interest to students and to newcomers in the field and its low cost will make it a compulsory reading for this target group.” (Timothy Noël, Angewandte Chemie International Edition, Vol. 54 (46), November, 2015)

• Kyoto University, Kyoto, Japan

  Jun-ichi Yoshida

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