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Inflammation and Immunity in Cancer

  • Book
  • © 2015

Overview

Editors:
  1. Tsukasa Seya

    1. Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

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  2. Misako Matsumoto

    1. Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

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  3. Keiko Udaka

    1. Kochi Medical School, Kochi University, Nankoku, Japan

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  4. Noriyuki Sato

    1. School of Medicine, Sapporo Medical University, Sapporo, Japan

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  • Facilitates a scientific understanding of up-to-date knowledge on cancer in immunotherapy

  • Includes information on recent Japanese studies of inflammation, immunity, and cancer

  • Is written by scientists directly involved in the field

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Role of Bone Marrow-Derived CCR1+ Cells in Colon Cancer Invasion and Metastasis

    • Makoto Mark Taketo
    Pages 1-11

  3. PGE2-Associated Inflammation and Gastrointestinal Tumorigenesis

    • Hiroko Oshima, Masanobu Oshima
    Pages 13-23

  4. The Role of Innate Immune Signaling in Regulation of Tumor-Associated Myeloid Cells

    • Hiroaki Shime, Misako Matsumoto, Tsukasa Seya
    Pages 25-47

  5. The Role of PIKfyve in Toll-Like Receptor-Mediated Responses

    • Kaoru Hazeki, Kiyomi Nigorikawa, Osamu Hazeki
    Pages 49-62

  6. Emerging Roles of an Innate Immune Regulator TAPE in the Toll-Like Receptor and RIG-I-Like Receptor Pathways

    • Kuan-Ru Chen, Pin Ling
    Pages 63-74

  7. Anchorage-Dependent Multicellular Aggregate Formation Induces CD44 High Cancer Stem Cell-Like Phenotypes in Adult T Cell Leukemia/Lymphoma Cells

    • Yukiko Miyatake, Masanori Kasahara
    Pages 75-84

  8. Innate Immune Receptor Signaling and IRF Family of Transcription Factors: Good Deeds and Misdeeds in Oncogenesis

    • Hiroaki Ikushima, Hideyuki Yanai, Tadatsugu Taniguchi
    Pages 85-101

  9. Host Factors Involved in the Propagation and Pathogenesis of Hepatitis C Virus

    • Toru Okamoto, Yoshiharu Matsuura
    Pages 103-108

  10. Hepatitis C Virus (HCV)-Induced Inflammation: The Role of Cross-Talk Between HCV-Infected Hepatocytes and Stellate Cells

    • Hironori Nishitsuji, Kenji Funami, Yuko Shimizu, Saneyuki Ujino, Tsukasa Seya, Kunitada Shimotohno
    Pages 109-121

  11. Development of Immunotherapy for Hepatocellular Carcinoma

    • Eishiro Mizukoshi, Shuichi Kaneko
    Pages 123-132

  12. Development of Glypican-3-Targeted Cancer Immunotherapy

    • Toshiaki Yoshikawa, Yu Sawada, Mayuko Yoshimura, Kazuya Ofuji, Tetsuya Nakatsura
    Pages 133-143

  13. The Vesicular Traffic System in Plasmacytoid Dendritic Cells as a Target for Immune Regulation

    • Norimitsu Kadowaki
    Pages 145-158

  14. In Vivo Targeting of Dendritic Cells with Artificial Adjuvant Vector Cells (aAVC) as a Novel Cancer Immunotherapy

    • Shin-ichiro Fujii, Jun Shinga, Satoru Yamasaki, Yusuke Sato, Miki Asakura, Kanako Shimizu
    Pages 159-164

  15. Enhancement of Efficacy of Wilms’ Tumor Gene WT1 Product-derived Peptide Cancer Vaccine by Co-administration with Immunopotentiating Agents: Lessons from Mouse Models

    • Hiroko Nakajima, Yoshihiro Oka, Akihiro Tsuboi, Fumihiro Fujiki, Naoya Tatsumi, Naoki Hosen et al.
    Pages 165-183

  16. Regulation of Antigen Presentation by Dendritic Cells and Its Application to Cancer Immunotherapy

    • Hidemitsu Kitamura, Junya Ohtake, Shun Kaneumi, Yosuke Ohno, Takuto Kishikawa, Satoshi Terada et al.
    Pages 185-196

  17. A New Mode of Cytotoxic T Lymphocyte Induction Secondary to Alteration of the Peptide/Major Histocompatibility Complex Class I Repertoire by Antigen Processing Defects

    • Takayuki Kanaseki, Yosuke Shionoya, Noriyuki Sato
    Pages 197-205

  18. Progress in Clinical Use of CC Chemokine Receptor 4 Antibody for Regulatory T Cell Suppression

    • Susumu Suzuki, Takashi Ishida, Kazuhiro Yoshikawa, Ryuzo Ueda
    Pages 207-227

  19. Adjuvant Immunotherapy for Cancer: From Basic Research to Clinical Bench

    • Misako Matsumoto, Masahiro Azuma, Tsukasa Seya
    Pages 229-241

  20. Immunological Regulation of Human Cancer Stem Cells/Cancer-Initiating Cells

    • Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Takayuki Kanaseki, Vitaly Kochin, Yasuaki Tamura et al.
    Pages 243-254
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Keywords

About this book

This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host immune response. The innate and acquired arms of the immune system mainly participate in tumor immune surveillance, and their activation is critically modulated by the situation of the tumor microenvironment. Many types of immune cells join the formation of the microenvironment. In particular, macrophages and dendritic cells enter the tumor mass to be main players in the inflammatory milieu of tumors. After introducing these topics, the book discusses immunotherapy for cancer patients as an outgrowth of this concept of infection and inflammation.

With the contributions of leading scientists actively involved in the field of antitumor immunity study, this book encourages readers to understand the mechanism of general cancers based on inflammation and will facilitate prevention and the development of therapeutics for cancer.

Editors and Affiliations

  • Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan

    Tsukasa Seya, Misako Matsumoto

  • Kochi Medical School, Kochi University, Nankoku, Japan

    Keiko Udaka

  • School of Medicine, Sapporo Medical University, Sapporo, Japan

    Noriyuki Sato

Bibliographic Information

  • Book Title: Inflammation and Immunity in Cancer

  • Editors: Tsukasa Seya, Misako Matsumoto, Keiko Udaka, Noriyuki Sato

  • DOI: https://doi.org/10.1007/978-4-431-55327-4

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Japan 2015

  • Hardcover ISBN: 978-4-431-55326-7Published: 08 April 2015

  • Softcover ISBN: 978-4-431-56336-5Published: 09 October 2016

  • eBook ISBN: 978-4-431-55327-4Published: 26 March 2015

  • Edition Number: 1

  • Number of Pages: XI, 268

  • Number of Illustrations: 12 b/w illustrations, 60 illustrations in colour

  • Topics: Immunology, Cancer Research, Oncology

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