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  • © 2013

Cortical Development

Neural Diversity and Neocortical Organization

  • Comprises state-of-the-art reviews on neural stem cell regulation and proneural gene functions

  • Provides details of the mechanisms of neuronal diversity and connectivity formation

  • Identifies new genes controlling synapse formation and higher brain functions

  • Includes supplementary material: sn.pub/extras

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii
  2. Dynamic Notch Signaling in Neural Progenitor Cells

    • Hiromi Shimojo, Yuki Maeda, Toshiyuki Ohtsuka, Ryoichiro Kageyama
    Pages 1-17
  3. Proneural Proteins and the Development of the Cerebral Cortex

    • Julian Heng, François Guillemot
    Pages 19-41
  4. Specification of GABAergic Neocortical Interneurons

    • Goichi Miyoshi, Robert P. Machold, Gord Fishell
    Pages 89-126
  5. Regulation of Cortical Circuit Formation

    • Fernanda M. Rodríguez-Tornos, Beatriz Cubelos, Marta Nieto
    Pages 127-151
  6. Neocortical Neurogenesis and Circuit Assembly

    • Peng Gao, Khadeejah T. Sultan, Xin-Jun Zhang, Song-Hai Shi
    Pages 153-180
  7. Synapse Formation in the Brain

    • Masayoshi Mishina, Tomoyuki Yoshida, Misato Yasumura, Takeshi Uemura
    Pages 229-247
  8. Genomic Imprinting in the Mammalian Brain

    • Wei-Chao Huang, Christopher Gregg
    Pages 249-261
  9. Genes Selectively Expressed in the Visual Cortex of the Old World Monkey

    • Yusuke Komatsu, Shigeko Toita, Masanari Ohtsuka, Toru Takahata, Shiro Tochitani, Tetsuo Yamamori
    Pages 263-276
  10. Back Matter

    Pages 277-282

About this book

This book reviews recent progress in cortical development research, focusing on the mechanisms of neural stem cell regulation, neuronal diversity and connectivity formation, and neocortical organization. Development of the cerebral cortex, the center for higher brain functions such as cognition, memory, and decision making, is one of the major targets of current research. The cerebral cortex is divided into many areas, including motor, sensory, and visual cortices, each of which consists of six layers containing a variety of neurons with different activities and connections. As this book explains, such diversity in neuronal types and connections is generated at various levels. First, neural stem cells change their competency over time, giving sequential rise to distinct types of neurons and glial cells: initially deep layer neurons, then superficial layer neurons, and lastly astrocytes. The activities and connections of neurons are further modulated via interactions with other brain regions, such as the thalamocortical circuit, and via input from the environment. This book on cortical development is essential reading for students, postdocs, and neurobiologists.

Editors and Affiliations

  • Institute for Virus Research, Kyoto University, Kyoto, Japan

    Ryoichiro Kageyama

  • Division of Brain Biology, National Institute for Basic Biology, Okazaki, Japan

    Tetsuo Yamamori

Bibliographic Information

  • Book Title: Cortical Development

  • Book Subtitle: Neural Diversity and Neocortical Organization

  • Editors: Ryoichiro Kageyama, Tetsuo Yamamori

  • DOI: https://doi.org/10.1007/978-4-431-54496-8

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Japan 2013

  • Hardcover ISBN: 978-4-431-54495-1Published: 10 October 2013

  • Softcover ISBN: 978-4-431-56117-0Published: 23 August 2016

  • eBook ISBN: 978-4-431-54496-8Published: 30 September 2013

  • Edition Number: 1

  • Number of Pages: VIII, 282

  • Number of Illustrations: 11 b/w illustrations, 56 illustrations in colour

  • Topics: Neurosciences, Developmental Biology, Cell Biology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access