Uric acid lithiasis

1. Front Matter

   Pages I-X

   PDF

2. Hyperuricemia-Epidemiology 1980

   • Georg Stockhausen

   Pages 1-3

3. Control of Purine Biosynthesis

   • James B. Wyngaarden

   Pages 5-7

4. Nutrition and Uric Acid Metabolism: Plasma Level, Turnover Excretion

   • W. Löffler, W. Gröbner, N. Zöllner

   Pages 8-18

5. Mechanisms of Purine Overproduction in Man

   • William N. Kelley

   Pages 19-24

6. Uric Acid Hyperproduction and Isohydric Steady-state in Gouty Patients

   • Peter Leskovar, R. Hartung, A. Siebert, E. Wellnhofer

   Pages 25-31

7. Juvenile Gout and Hyperuricosuria Due to Chronic Compensated Hemolytic Syndrome

   • U. A. Liberman, R. Samuel, A. Halabe, O. Sperling

   Pages 32-35

8. Renal Excretion of Urate in Mammals

   • Françoise Roch-Ramel, Christian Schäli

   Pages 36-42

9. Relation Between Urate Transport and Tubular Flow Rate in Rat and Man

   • P. Deetjen, F. Lang, R. Greger

   Pages 43-47

10. Renal Tubular Handling of Urate in Calcium Stone Formers with Hyperuricosuria or Renal Acidification Defects

    • B. Fellström, U. Backman, B. G. Danielson, G. Johansson, S. Ljunghall, B. Wikström

    Pages 48-51

11. ‘Uric Add’ Stones in Children: Problems of Diagnosis and Treatment in a New Defect— Adenine Phosphoribosyltransferase Deficiency

    • H. A. Simmonds, J. S. Cameron, M. J. Dillon, T. M. Barratt, K. J. Van Acker

    Pages 52-57

12. Complete Adenine Phosphoribosyltransferase Deficiency with 2,8-Dihydroxyadenine Stone Formation

    • J. Joost, F. Schabel, W. Doppler

    Pages 58-65

13. Idiopathic Uric Acid Lithiasis — Some Less Known Epidemiologie and Metabolic Findings

    • Dieter Scholz, P. O. Schwille, W. Engelhardt, A. Sigel

    Pages 66-69

14. The Contribution of Dietary Purines to Urinary Urate Excretion in Gouty and Renal Stone Patients

    • A. Halabe, R. Samuel, U. A. Liberman, O. Sperling

    Pages 70-74

15. Results of Examination in Renal Stone formers after Purine Load

    • Bernhard Lux, Jess. Braun, P. May

    Pages 75-80

16. Latent hyperuricemia and hyperuricosuria—a risk factor for stone formation—diagnosis with a purine-loading test

    • A. Hesse, W. Schneeberger, D. Bach, W. Dewes, W. Vahlensieck

    Pages 81-87

17. Laboratory Analysis of the Results of Treatment of Uric Acid Stones. “Zyloric U”—a New Insight (?)

    • K. Jarrar, W. Guttmann

    Pages 88-90

18. The Action of a Benzbromarone-Citrate Preparation on Lithogenous and Inhibitory Substances

    • D. Bach, A. Hesse, A. Strenge, W. Vahlensieck

    Pages 91-98

19. Pathogenesis and Incidence of Calcium-containing and Pure Uric Acid Stones in Patients with Hyperuricemia and Hyperurocosuria

    • Peter May, B. Lux, J. Braun

    Pages 99-105

20. Clinical Characteristics of the Calcium Stone Disease in Hyperuricosuria

    • U. Backman, B. G. Danielson, B. Fellström, G. Johansson, S. Ljunghall, B. Wikström

    Pages 106-109

Kidney stones is a common and ancient disease. Yet, many questions concerning their etiology, treatment, and prevention are still open. The Harnstein-Symposien Bonn-Wien is an organization designed to bring together scientists from the various fields relevant to urolithiasis: medicine, urology, biochemistry, etc. In the framework of this organiza­ tion an International Workshop was held in Tel Aviv on December 10 and 11 1980 to discuss the various aspects of uric acid lithiasis. Uric acid stones have been known to mankind for thousands of years. Urate-contain­ ing stones were found in Egyptian mummies and in a three-thousand-year old mummy from Arizona. Evidently, with the constant increase in standard of living, associated with increased amount of purine intake, which we are facing in this century, the fre­ quency of uric acid lithiasis is on the increase. In the second half of this century, signi­ ficant progress has been made in the knowledge of the mechanisms of uric acid over­ production, as well as in the understanding of the etiology, prevention, and tretament of uric acid stones. As a result, uric acid lithiasis can be prevented and when present it can be treated well. Moreover most uric acid stones can be dissolved in vivo. This workshop included reviews from some of the leading authorities on the various aspects of uric acid metabolism in man: biochemistry, pathology, renal handling, nutri­ tion, etc. , and these reviews and results of new studies are presented here.

• Laboratory
• biochemistry
• biosynthesis
• calcium
• diagnosis
• etiology
• kidney
• medicine
• nutrition
• pathology
• plasma
• prevention
• production
• treatment
• urology

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