Overview
- Relevant leukocyte and endothelial adhesion molecules are discussed
- Written by leaders in the field
- Provides outlook on future therapies
- Includes supplementary material: sn.pub/extras
Part of the book series: Progress in Inflammation Research (PIR)
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Table of contents (13 chapters)
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Front Matter
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Capture and rolling
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Front Matter
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Firm adhesion
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Front Matter
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Transendothelial migration
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Front Matter
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Back Matter
Keywords
About this book
Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most relevant leukocyte and endothelial adhesion molecules. The chapters are written by leaders in the field and focus on the biology, structure, function, and regulation of adhesion molecules. Currently approved adhesion molecule-based therapies are reviewed and an outlook for future approaches is also provided.
The book is of interest to clinicians and scientists from immunology, physiology, cancer research, rheumatology, allergology, infectious diseases, gastroenterology, pulmonology and cardiology.
Reviews
From the reviews:
“This book is a great and informative text to all those who wish to access and demystify the field of adhesion molecules. The monograph … deals specifically with adhesion molecules in the whole process of leukocyte extravasation with a focus on inflammation. … this is a well-organised and highly informative text. … it provides food for thought relevant to the application of current knowledge. … this is an eminently accessible and readable volume.” (Andrew Devitt, Inflammation Research, Vol. 59, 2010)Editors and Affiliations
Bibliographic Information
Book Title: Adhesion Molecules: Function and Inhibition
Editors: Klaus Ley
Series Title: Progress in Inflammation Research
DOI: https://doi.org/10.1007/978-3-7643-7975-9
Publisher: Birkhäuser Basel
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Birkhäuser Basel 2007
Hardcover ISBN: 978-3-7643-7974-2Published: 16 August 2007
eBook ISBN: 978-3-7643-7975-9Published: 27 October 2007
Series ISSN: 1422-7746
Series E-ISSN: 2296-4525
Edition Number: 1
Number of Pages: XIV, 309
Number of Illustrations: 22 b/w illustrations, 1 illustrations in colour
Topics: Immunology, Cell Biology, Infectious Diseases, Pharmacology/Toxicology