Overview
- Presents new essential technologies
- Critical evaluation of new biomarkers
- Regulatory issues and potential pitfalls are discussed
Part of the book series: Progress in Drug Research (PDR, volume 62)
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Table of contents (10 chapters)
Keywords
About this book
In this monograph the contribution of imaging modalities to the various stages of drug discovery and development, from early target validation to their use in clinical development programs, is described. Chapters are devoted to the description of the drug discovery process as such, to the various imaging modalities being used both preclinically and clinically, to applications of imaging during the optimization of a lead compound (addressing issues such as bioavailability and efficacy) and during the drug safety evaluation. A chapter describes imaging biomarkers, their development, advantages and the potential pitfalls associated with their use. In the translation of imaging tools from animals to man regulatory issues have to be addressed, which are dealt with in a separate section.
The monograph provides a comprehensive overview on the role of imaging in drug discovery today and discusses major developments and trends both with regard to technologies and applications.
Editors and Affiliations
Bibliographic Information
Book Title: Imaging in Drug Discovery and Early Clinical Trials
Editors: Paul L. Herrling, Alex Matter, Markus Rudin
Series Title: Progress in Drug Research
DOI: https://doi.org/10.1007/3-7643-7426-8
Publisher: Birkhäuser Basel
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Birkhäuser Basel 2005
eBook ISBN: 978-3-7643-7426-6Published: 17 January 2006
Series ISSN: 0071-786X
Series E-ISSN: 2297-4555
Edition Number: 1
Number of Pages: X, 392
Number of Illustrations: 61 b/w illustrations, 26 illustrations in colour
Topics: Imaging / Radiology, Control, Robotics, Mechatronics