Skip to main content
  • Book
  • © 2006

NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics

Birkhäuser
  • Comprehensive state-of-the art review
  • Discusses the frontiers of NPY research and drug development
  • Points out new opportunities for medical intervention

Part of the book series: Experientia Supplementum (EXS, volume 95)

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (19 chapters)

  1. Front Matter

    Pages I-IX
  2. Introduction

    1. Front Matter

      Pages 1-1
  3. NPY family of peptides, receptors and processing enzymes

    1. Front Matter

      Pages 5-5
    2. Molecular ligand-receptor interaction of the NPY/PP peptide family

      • Nicole Merten, Annette G. Beck-Sickinger
      Pages 35-62
  4. Physiological and pathophysiological perspectives of the NPY family of peptides

    1. Front Matter

      Pages 63-63
    2. Modulator role of neuropeptide Y in human vascular sympathetic neuroeffector junctions

      • M. Verónica Donoso, Ana María Delpiano, J. Pablo Huidobro-Toro
      Pages 65-76
    3. Neuropeptide Y and the cerebral circulation

      • Lars Edvinsson
      Pages 105-112
    4. Role of neuropeptide Y in the regulation of kidney function

      • Joseph Winaver, Zaid Abassi
      Pages 123-132
    5. NPY and neuron-adipocyte interactions in the regulation of metabolism

      • L. Christine Turtzo, M. Daniel Lane
      Pages 133-141
    6. NPY and energy homeostasis: an opportunity for novel anti-obesity therapies

      • Douglas J. MacNeil, Akio Kanatani
      Pages 143-156
    7. NPY and bone

      • Susan J. Allison, Herbert Herzog
      Pages 171-182
    8. NPY in alcoholism and psychiatric disorders

      • Annika Thorsell, Rose-Marie Karlsson, Markus Heilig
      Pages 183-192
    9. NPY and extreme stress: lessons learned from posttraumatic stress disorder

      • Mary Ann Dutton, Edward W. Lee, Zofia Zukowska
      Pages 213-222

About this book

The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists which are in clinical development for obesity while NPY Y1 receptors are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders are also actively pursued.

This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders, written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.

Editors and Affiliations

  • Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC, USA

    Zofia Zukowska

  • Wyeth Research, Collegeville, USA

    Giora Z. Feuerstein

Bibliographic Information

  • Book Title: NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics

  • Editors: Zofia Zukowska, Giora Z. Feuerstein

  • Series Title: Experientia Supplementum

  • DOI: https://doi.org/10.1007/3-7643-7417-9

  • Publisher: Birkhäuser Basel

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Birkhäuser Basel 2006

  • Hardcover ISBN: 978-3-7643-7155-5Published: 17 November 2005

  • eBook ISBN: 978-3-7643-7417-4Published: 28 March 2006

  • Series ISSN: 1664-431X

  • Series E-ISSN: 2504-3692

  • Edition Number: 1

  • Number of Pages: X, 280

  • Topics: Biomedicine general

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access