Overview
- Potential use of regulatory T cells as targets for immunotherapy (diabetes, multiple sclerosis, RA, IBD)
- Focus on CD4+/CD25+ regulatory T-cells
- International authorship
- Includes supplementary material: sn.pub/extras
Part of the book series: Progress in Inflammation Research (PIR)
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Table of contents (12 chapters)
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Origin, function and distribution of regulatory T cells
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The potential use of regulatory T cells in immunotherapy
Keywords
About this book
Regulatory T-cells are essential components of the immune system, and several different subsets of regulatory T-cells have been described. Considerable regulatory function has been attributed to the CD4+CD25+ T-cell subset. These cells act by suppressing adaptive and possibly innate immune responses thereby maintaining or restoring the balance between immunity and tolerance. The suppressive effects of CD4+CD25+ regulatory T-cells are cell-contact dependent.
Recent developments and viewpoints in the field of CD4+CD25+ regulatory T-cells as well as the potential use of regulatory T-cells in immunotherapy of inflammatory diseases are discussed in this volume. By linking data from experimental models with recent findings from the clinic, this book will be of interest to immunologists and other biomedical researchers as well as clinicians interested in the regulation and manipulation of the immune response during inflammatory disease.
Editors and Affiliations
Bibliographic Information
Book Title: Regulatory T Cells in Inflammation
Editors: Leonie S. Taams, Marca H. M. Wauben, Arne N. Akbar
Series Title: Progress in Inflammation Research
DOI: https://doi.org/10.1007/b137037
Publisher: Birkhäuser Basel
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Birkhäuser Basel 2005
Hardcover ISBN: 978-3-7643-7088-6Published: 22 March 2005
eBook ISBN: 978-3-7643-7301-6Published: 30 March 2006
Series ISSN: 1422-7746
Series E-ISSN: 2296-4525
Edition Number: 1
Number of Pages: XI, 240
Topics: Immunology, Pharmacology/Toxicology, Internal Medicine, Endocrinology, Cell Biology