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Recent Advances in Neuropharmacology

  • Conference proceedings
  • © 1991

Overview

Editors:
  1. H. Bönisch

    1. Institute of Pharmacology and Toxicology, University of Bonn, Federal Republic of Germany

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  2. K.-H. Graefe

    1. Institute of Pharmacology and Toxicology, University of Würzburg, Federal Republic of Germany

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  3. S. Z. Langer

    1. Department of Biology, Synthélabo Recherche (LERS), Paris, France

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  4. E. Schömig

    1. Institute of Pharmacology and Toxicology, University of Würzburg, Federal Republic of Germany

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Part of the book series: Journal of Neural Transmission. Supplementa (NEURAL SUPPL, volume 34)

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Table of contents (27 papers)

  1. Front Matter

    Pages I-VIII
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  2. Synthesis and inactivation of neurotransmitters

    1. Front Matter

      Pages 1-1
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    2. The effects of electroconvulsive shock on catecholamine function in the locus ceruleus and hippocampus

      • N. Weiner, M. A. Hossain, J. M. Masserano
      Pages 3-9

    3. Molecular aspects of the neuronal noradrenaline transporter

      • H. Bönisch, G. Paulus, G. Martiny-Baron, B. Lingen, D. Coppeneur
      Pages 11-17

    4. Energy requirements for the basal efflux of noradrenaline and its metabolites from adrenergic varicosities

      • U. Trendelenburg, H. Russ, E. Schömig
      Pages 19-25

    5. The effects of type 1 diabetes mellitus and of tobacco smoke on dissipation of catecholamines in pulmonary endothelial cells — a non-neuronal site of uptake1

      • L. J. Bryan-Lluka, G. J. McKee
      Pages 27-35

    6. Distribution of extraneuronal uptake1 in reproductive tissues: studies on cells in culture

      • I. S. de la Lande, V. Marino, T. Lavranos, J. A. Kennedy, D. A. S. Parker, R. F. Seamark
      Pages 37-42

    7. Extraneuronal inactivation of noradrenaline in tissue culture

      • E. Schömig, J. Babin-Ebell, M. Gliese, H. Russ
      Pages 43-49

    8. The influence of the estrous cycle on the accumulation of 3H-noradrenaline in rat uterus and on efflux of radioactivity from the uterus

      • S. Pluchino, I. Negrón
      Pages 51-59

    9. PC12 cells as a window for the differentiation of neural crest into adrenergic nerve ending and adrenal medulla

      • M. B. H. Youdim
      Pages 61-67

    10. Clinical aspects on presynaptic noradrenaline metabolism

      • J. Ludwig, T. Halbrügge, K.-H. Graefe
      Pages 69-75

    11. Effects of imipramine and some tryptamine derivatives on the efflux of 3H-5-hydroxytryptamine from rabbit platelets

      • K.-H. Graefe, R. Wölfel
      Pages 77-83

    12. Influence of antidepressant drugs on seizure susceptibility and the anticonvulsant activity of valproate in mice

      • Z. Kleinrok, J. Gustaw, S. J. Czuczwar
      Pages 85-90

  3. Neurotransmitter release and co-transmission

    1. Front Matter

      Pages 91-91
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    2. Noradrenaline-ATP corelease and cotransmission following activation of nicotine receptors at postganglionic sympathetic axons

      • K. Starke, R. Bültmann, J. M. Bulloch, I. von Kügelgen
      Pages 93-98

    3. Preliminary evidence for noradrenaline and ATP as neurotransmitters in the porcine isolated palmar common digital artery

      • V. G. Wilson, N. A. Blaylock
      Pages 99-105

    4. Involvement of catecholaminergic neurones of the nucleus of the solitary tract (NTS) in blood pressure regulation

      • A. Philippu, A. Pfitscher, N. Singewald
      Pages 107-112

    5. Vasodilatation by endothelium-derived nitric oxide as a major determinant of noradrenaline release

      • T. Halbrügge, K. Lütsch, A. Thyen, K.-H. Graefe
      Pages 113-119

    6. Stimulation of noradrenaline release in the cerebral cortex via presynaptic N-methyl-D-aspartate (NMDA) receptors and their pharmacological characterization

      • M. Göthert, K. Fink
      Pages 121-127

    7. Presynaptic modulation of neurotransmitter release by endogenous angiotensin II in brown adipose tissue

      • L. A. Cassis, L. P. Dwoskin
      Pages 129-137
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About this book

This volume is dedicated to Professor Ullrich Trendelenburg. It contains the proceedings of a symposium which was held in his honour on the occasion of his retirement and took place March 22-24, 1991 in Wiirzburg. Ullrich Trendelenburg was the head of the Department of Pharmacology at Wiirzburg University from 1968 till the end of March 1991. He is famous internationally for his contributions to the physiology and pharmacology of the autonomic nervous system, and his impact on pharmacology in general throughout the world has been outstanding. The various phases of his life and his career have been delineated recently by Youdim and Riederer (Journal of Neural Transmission; Suppl. 32, 1990). The articles included in this volume reflect a considerable range of current research work dealing with various aspects of neuropharmacology, i. e. , the field of research Ullrich Trendelenburg has influenced most. One or more authors of each chapter are either former or present students and coworkers or close friends of Ullrich Trendelenburg. The first section is devoted to the synthesis and metabolism of catecholamines as well as to the mechanisms by which amine transmitters are removed from the extracellular fluid; three chapters deal with the two types of extraneuronal uptake of catecholamines. The second section concentrates on the release of catecholamines in the peripheral and the central nervous system, the regulation of transmitter release and the noradrenaline-ATP co-transmis­ sion. The third section deals with the pharmacology of various receptors, including agrenoceptors, adenosine, 5-HT and glutamate receptors.

Editors and Affiliations

  • Institute of Pharmacology and Toxicology, University of Bonn, Federal Republic of Germany

    H. Bönisch

  • Institute of Pharmacology and Toxicology, University of Würzburg, Federal Republic of Germany

    K.-H. Graefe, E. Schömig

  • Department of Biology, Synthélabo Recherche (LERS), Paris, France

    S. Z. Langer

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