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Prevention and Treatment of Delayed Ischaemic Dysfunction in Patients with Subarachnoid Haemorrhage

An Update

  • Book
  • © 1988

Overview

Editors:
  1. Hans-Jürgen Reulen

    1. Department of Neurosurgery, University Hospital, Inselspital, Bern, Switzerland

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  2. Jacques Philippon

    1. Department of Neurosurgery, C.H.U. Pitié-Salpêtrière, Paris, France

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Acta Neurochirurgica Supplement (NEUROCHIRURGICA, volume 45)

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Table of contents (8 chapters)

  1. Front Matter

    Pages I-VII
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  2. Pathophysiology of Subarachnoid Haemorrhage

    • B. Voldby
    Pages 1-6

  3. Pathophysiology of Delayed Ischaemic Dysfunction After Subarachnoid Haemorrhage: Experimental and Clinical Data

    • A. D. Mendelow
    Pages 7-10

  4. Cerebrovascular and Cerebral Effects of Nimodipine — an Update

    • L. Brandt, K.-E. Andersson, B. Ljunggren, H. Säveland, T. Ryman
    Pages 11-20

  5. Haemodynamic Effectiveness of Nimodipine on Spastic Brain Vessels After Subarachnoid Haemorrhage Evaluated by the Transcranial Doppler Method

    • A. Harders, J. Gilsbach
    Pages 21-28

  6. Interactions Between Nimodipine and General Anaesthesia — Clinical Investigations in 124 Patients During Neurosurgical Operations

    • H. Müller, H. Kafurke, P. Marck, J. Zierski, G. Hempelmann
    Pages 29-35

  7. Attempts at Prevention and Treatment of Delayed Ischaemic Dysfunction in Patients with Subarachnoid Haemorrhage

    • Robert H. Wilkins
    Pages 36-40

  8. Nimodipine in the Prevention of Ischaemic Deficits After Aneurysmal Subarachnoid Haemorrhage

    • Joachim M. Gilsbach
    Pages 41-50

  9. Review of Treatment of Symptomatic Cerebral Vasospasm with Nimodipine

    • F. Buchheit, P. Boyer
    Pages 51-55
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Keywords

About this book

During the last meeting of the European Association of Neurosurgical Societies (Barcelona 7-16 September 1987), a Symposium was devoted to the use of calcium antagonists in cerebral vasospasm. As shown by its title "Prevention and treatment of delayed ischaemic dysfunction in patients with subarachnoid haemorrhage: an update", papers presented at the Symposium covered a broad spectrum from some basic data on pathophysiology of subarachnoid haemorrhage (SAH) and delayed ischaemic dysfunction, to the clinical use of nimodipine, which has been largely documented among calcium inhibitors for its cerebrovascular properties. This supplementum of Acta Neurochirurgica is based upon the papers presented. Some articles, however, have been extended to take into account further results in order to present a broad view of the subject. The Symposium started with two presentations concerning general aspects of SAH: in the first one, B. Voldby reviewed the pathophysiological events following SAH: if modifications of intracranial pressure (ICP) and decrease of cerebral blood flow (CBF) are the primary alterations, metabolic changes (particularly reduction in CMR0 ) 2 contribute rapidly to disturbances of brain circulation. A variety of mechanisms may be responsible for the neurological dysfunction: most of them are directly related to the reduction in cerebral perfusion pressure (CPP) which may result in ischaemia. This fall in CPP (either due to elevation of ICP or reduction of mean arterial blood pressure) is observed under different pathophysiological conditions, discussed in the paper by A. D. Mendelow.

Editors and Affiliations

  • Department of Neurosurgery, University Hospital, Inselspital, Bern, Switzerland

    Hans-Jürgen Reulen

  • Department of Neurosurgery, C.H.U. Pitié-Salpêtrière, Paris, France

    Jacques Philippon

Bibliographic Information

  • Book Title: Prevention and Treatment of Delayed Ischaemic Dysfunction in Patients with Subarachnoid Haemorrhage

  • Book Subtitle: An Update

  • Editors: Hans-Jürgen Reulen, Jacques Philippon

  • Series Title: Acta Neurochirurgica Supplement

  • DOI: https://doi.org/10.1007/978-3-7091-9014-2

  • Publisher: Springer Vienna

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag/Wien 1988

  • Softcover ISBN: 978-3-211-82096-4Published: 29 December 1988

  • eBook ISBN: 978-3-7091-9014-2Published: 06 December 2012

  • Series ISSN: 0065-1419

  • Series E-ISSN: 2197-8395

  • Edition Number: 1

  • Number of Pages: VII, 55

  • Number of Illustrations: 19 b/w illustrations

  • Topics: Neurosurgery, Neurology, Neurosciences, Pharmacology/Toxicology, Rehabilitation

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