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  • Conference proceedings
  • © 1994

Progressive Supranuclear Palsy: Diagnosis, Pathology, and Therapy

Part of the book series: Journal of Neural Transmission. Supplementa (NEURAL SUPPL, volume 42)

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Table of contents (22 papers)

  1. Front Matter

    Pages I-X
  2. Clinical aspects

    1. Front Matter

      Pages 1-1
    2. Historical notes

      • John C. Steele
      Pages 3-14
    3. The auditory startle response in progressive supranuclear palsy

      • J. C. Rothwell, M. Vidailhet, P. D. Thompson, A. J. Lees, C. D. Marsden
      Pages 43-50
    4. Differential diagnosis of PSP

      • R. C. Duvoisin
      Pages 51-67
  3. Neuroimage analysis, cerebral blood flow and metabolism

    1. Front Matter

      Pages 91-91
    2. Magnetic resonance imaging in progressive supranuclear palsy and other parkinsonian disorders

      • M. Savoiardo, F. Girotti, L. Strada, E. Ciceri
      Pages 93-110
    3. Clinical progressive supranuclear palsy: differential diagnosis by IBZM-SPECT and MRI

      • G. Arnold, K. Tatsch, W. H. Oertel, Th. Vogl, J. Schwarz, E. Kraft et al.
      Pages 111-118
  4. Morphological aspects

    1. Front Matter

      Pages 135-135
    2. Neurofibrillary pathology in progressive supranuclear palsy (PSP)

      • J. Cervós-Navarro, K. Schumacher
      Pages 153-164
    3. Cortical tangles in progressive supranuclear palsy

      • M. Verny, C. Duyckaerts, P. Delaère, Y. He, J.-J. Hauw
      Pages 179-188
    4. Vascular progressive supranuclear palsy

      • J. Winikates, J. Jankovic
      Pages 189-201
  5. Biochemical aspects

    1. Front Matter

      Pages 203-203

About this book

When Steele, Richardson and Olszewski described Progressive Supranuclear Palsy in Archives of Neurology in 1964, it was thought to be a rare disease. Recent pathological studies of large numbers of patients diagnosed as having Parkinson's disease in life have highlighted the fact that at least one in ten of such cases have some other condition. Progressive Supranuclear Palsy is one of the commonest alternative diagnoses. This book is therefore a timely review of present understanding of Progressive Supranuclear Palsy. Much has been learnt about this sporadic illness of middle and late life although its cause remains unknown, and its treatment continues to be difficult. The Editors have selected a team of authors who review the clinical aspects, neuro-imaging find­ ings, neuropathology, neurochemistry, epidemiology, and therapy of Progres­ sive Supranuclear Palsy. All are to congratulated on producing an excellent and detailed picture of contemporary knowledge of the condition. Anyone interested in Progressive Supranuclear Palsy cannot do better than to start by reading this book. It is to be hoped that it will prompt further investigation to establish its cause and cure. C. D. MARSDEN, London Preface Progressive Supranuclear Palsy (PSP) is a neurodegenerative disorder charac­ terized clinically by the appearance of a supranuclear gaze palsy and extra­ pyramidal features which include bradykinesia and axial dystonia. Postural instability and falls and frontal-type behavioural and cognitive disturbances complete the clinical picture of this progressive disorder.

Editors and Affiliations

  • Neurology Service, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain

    E. Tolosa

  • Neurology Service, Robert Wood Johnson University Hospital, New Brunswick, USA

    R. Duvoisin

  • Neurological Tissue Bank, Faculty of Medicine, University of Barcelona, Spain

    F. F. Cruz-Sánchez

Bibliographic Information

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access