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Ageing and Dementia

Current and Future Concepts

  • Conference proceedings
  • © 2002
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Overview

Editors:
  1. Kurt A. Jellinger

    1. Institut für Klinische Neurobiologie, Wien, Austria

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  2. Reinhold Schmidt

    1. Universitätsklinik für Neurologie, Graz, Austria

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    You can also search for this editor in PubMed   Google Scholar

  3. Manfred Windisch

    1. JWS Research Forschungslabor GmbH, Graz, Austria

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Journal of Neural Transmission. Supplementa (NEURAL SUPPL, volume 62)

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Table of contents (33 papers)

  1. Front Matter

    Pages I-VIII
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  2. Vascular-ischemic dementia: an update

    • K. A. Jellinger
    Pages 1-23
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  3. Frequency of white matter lesions and silent lacunar infarcts

    • E. J. van Dijk, N. D. Prins, S. E. Vermeer, P. J. Koudstaaf, M. M. B. Breteler
    Pages 25-39
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  4. CT and MRI rating of white matter changes

    • P. Kapeller, R. Schmidt, Ch. Enzinger, S. Ropele, F. Fazekas
    Pages 41-45
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  5. Risk factors and progression of small vessel disease-related cerebral abnormalities

    • R. Schmidt, F. Fazekas, C. Enzinger, S. Ropele, P. Kapeller, H. Schmidt
    Pages 47-52
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  6. Microangiopathy-related cerebral damage and angiotensinogen gene: from epidemiology to biology

    • H. Schmidt, F. Fazekas, R. Schmidt
    Pages 53-59
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  7. Can small-vessel disease-related cerebral abnormalities be used as a surrogate marker for vascular dementia trials?

    • F. Fazekas, S. Ropele, R. Schmidt
    Pages 61-67
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  8. Reactive oxygen: its sources and significance in Alzheimer disease

    • G. Perry, A. Nunomura, A. D. Cash, M. A. Taddeo, K. Hirai, G. Aliev et al.
    Pages 69-75
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  9. Dysregulation of neuronal differentiation and cell cycle control in Alzheimer’s disease

    • T. Arendt
    Pages 77-85
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  10. A broader horizon of Alzheimer pathogenesis: ALZAS — an early serum biomarker?

    • E. Kienzl, K. Jellinger, B. Janetzky, H. Steindl, J. Bergmann
    Pages 87-95
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  11. Is mild cognitive impairment bridging the gap between normal aging and Alzheimer’s disease?

    • G. Smith
    Pages 97-104
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  12. Vienna Transdanube Aging “VITA”: study design, recruitment strategies and level of participation

    • P. Fischer, S. Jungwirth, W. Krampla, S. Weissgram, W. Kirchmeyr, W. Schreiber et al.
    Pages 105-116
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  13. Conversion from preclinical to clinical stage of Alzheimer’s disease as shown by decline of cognitive function in carriers of the Swedish APP-mutation

    • O. Almkvist, K. Axelman, H. Basun, L.-O. Wahlund, L. Lannfelt
    Pages 117-125
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  14. The role of biological markers in the early and differential diagnosis of Alzheimer’s disease

    • A. Kurz, M. Riemenschneider, A. Drzezga, N. Lautenschlager
    Pages 127-133
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  15. Measuring cognition in advanced Alzheimer’s disease for clinical trials

    • F. A. Schmitt, D. Cragar, J. W. Ashford, B. Reisberg, S. Ferris, H.-J. Möbius et al.
    Pages 135-148
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  16. Current drugs and future hopes in the treatment of Alzheimer’s disease

    • M. Windisch, B. Hutter-Paier, E. Schreiner
    Pages 149-164
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  17. Development of human antibody fragments directed towards synaptic acetylcholinesterase using a semi-synthetic phage display library

    • C. Flores-Flores, A. Nissim, S. Shochat, H. Soreq
    Pages 165-179
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  18. Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer’ disease

    • E. Giacobini
    Pages 181-187
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  19. Impact of muscarinic agonists for successful therapy of Alzheimer’s disease

    • A. Fisher, R. Brandeis, R. Haring, N. Bar-Ner, M. Kliger-Spatz, N. Natan et al.
    Pages 189-202
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  20. Nicotinic receptor modulation: Advantages for successful Alzheimer’s disease therapy

    • H. Geerts, L. Finkel, R. Carr, A. Spiros
    Pages 203-216
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Keywords

About this book

Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.

Editors and Affiliations

  • Institut für Klinische Neurobiologie, Wien, Austria

    Kurt A. Jellinger

  • Universitätsklinik für Neurologie, Graz, Austria

    Reinhold Schmidt

  • JWS Research Forschungslabor GmbH, Graz, Austria

    Manfred Windisch

Bibliographic Information

  • Book Title: Ageing and Dementia

  • Book Subtitle: Current and Future Concepts

  • Editors: Kurt A. Jellinger, Reinhold Schmidt, Manfred Windisch

  • Series Title: Journal of Neural Transmission. Supplementa

  • DOI: https://doi.org/10.1007/978-3-7091-6139-5

  • Publisher: Springer Vienna

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Wien 2002

  • Hardcover ISBN: 978-3-211-83797-9Published: 20 August 2002

  • Softcover ISBN: 978-3-211-83796-2Published: 20 August 2002

  • eBook ISBN: 978-3-7091-6139-5Published: 28 June 2011

  • Series ISSN: 0303-6995

  • Edition Number: 1

  • Number of Pages: VIII, 384

  • Additional Information: Special edition of Journal of Neural Transmission, Supplement 62, 2002

  • Topics: Neurology, Psychiatry, Neurosciences, Pharmacology/Toxicology

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