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Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures

  • Book
  • © 2012

Overview

Authors:
  1. Jaroslav Sebestik

    1. AS CR, Department of Molecular Spectroscopy, Inst. of Organic Chemistry, Biochemistry, Prague, Czech Republic

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    You can also search for this author in PubMed   Google Scholar

  2. Milan Reinis

    1. Institute of Molecular Genetics AS CR, Prague, Czech Republic

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    You can also search for this author in PubMed   Google Scholar

  3. Jan Jezek

    1. , Laboratory of Glycoconjugates, Inst. of Organic Chemistry, Biochemistry, Prague, Czech Republic

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    You can also search for this author in PubMed   Google Scholar

  • Multidisciplinary approach to the field

  • Up to date and condensed information

  • Leads from basic organic chemistry research to biomedical and medical application

  • Includes supplementary material: sn.pub/extras

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Introduction

    • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
    Pages 1-5

  3. Chemistry and Structure of Dendrimers

    1. Front Matter

      Pages 7-7
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  4. Chemistry and structure of dendrimers

    1. Definition of Terms and Nomenclature

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 9-22

    2. Sugar Code (Glycocode)

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 23-27

    3. Classes of Peptide-, Glyco-, and Glycopeptide Dendrimers

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 29-44

    4. The Dendritic State and Dendritic Effects

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 45-54

    5. Synthesis of Dendrimers: Convergent and Divergent Approaches

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 55-81

    6. Purification and Characterization of Dendrimers

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 83-92

    7. Dendrimeric Libraries

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 93-98

    8. Dendrimers in Catalysis

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 99-102

  5. Dendrimers and Their Biological and Therapeutic Applications

    1. Front Matter

      Pages 103-103
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  6. Dendrimers and their biological and therapeutic applications

    1. Dendrimers and Solubility

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 105-109

    2. Biocompatibility and Toxicity of Dendrimers

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 111-114

    3. Dendrimers in Nanoscience and Nanotechnology

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 115-129

    4. Dendrimers in Drug Delivery

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 131-140

    5. Dendrimers in Gene Delivery

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 141-147

    6. Dendrimers and Bacteria

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 149-159

    7. Dendrimers and Viruses

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 161-170

    8. Dendrimers and Parasites

      • Jaroslav Å ebestík, Milan ReiniÅ¡, Jan Ježek
      Pages 171-173
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Keywords

About this book

Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers.

Authors and Affiliations

  • AS CR, Department of Molecular Spectroscopy, Inst. of Organic Chemistry, Biochemistry, Prague, Czech Republic

    Jaroslav Sebestik

  • Institute of Molecular Genetics AS CR, Prague, Czech Republic

    Milan Reinis

  • , Laboratory of Glycoconjugates, Inst. of Organic Chemistry, Biochemistry, Prague, Czech Republic

    Jan Jezek

Bibliographic Information

  • Book Title: Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures

  • Authors: Jaroslav Sebestik, Milan Reinis, Jan Jezek

  • DOI: https://doi.org/10.1007/978-3-7091-1206-9

  • Publisher: Springer Vienna

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Wien 2012

  • Hardcover ISBN: 978-3-7091-1205-2Published: 13 December 2012

  • Softcover ISBN: 978-3-7091-1703-3Published: 29 January 2015

  • eBook ISBN: 978-3-7091-1206-9Published: 13 December 2012

  • Edition Number: 1

  • Number of Pages: XVIII, 238

  • Topics: Molecular Medicine, Biomedicine general, Pharmaceutical Sciences/Technology

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