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Clinical Aspects and Laboratory. Iron Metabolism, Anemias

Concepts in the anemias of malignancies and renal and rheumatoid diseases

  • Conference proceedings
  • © 2011

Overview

Authors:
  1. Manfred Wick

    1. Institute of Clinical Chemistry, Klinikum Grosshadern, University of Munich, Germany

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  2. Wulf Pinggera

    1. Maria Taferl, Austria

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  3. Paul Lehmann

    1. Mainz, Germany

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  • considers recent advances in diagnosis and therapy of the anemias;

  • update on research findings on iron deficiency as the most important cause of anemia and associated topics;

  • new emphasis on anemias of chronic disease (ACD) and renal anemias

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Table of contents (11 papers)

  1. Front Matter

    Pages I-X
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  2. Introduction

    1. Introduction

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 1-2

  3. Fundamentals

    1. Iron Metabolism

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 3-16

    2. Erythropoiesis

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 17-23

    3. Disturbances of Iron Metabolism/Disturbances of Erythropoiesis and Hemolysis

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 24-49

  4. Clinical Aspects

    1. Diagnosis of Disturbances of Iron Metabolism

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 50-67

    2. Iron Deficiency — Diagnosis and Therapy

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 68-79

    3. Disturbances of Iron Distribution and Hypochromic Anemias

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 80-105

    4. Disturbances of Iron Utilization

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 106-112

    5. Iron Overload

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 113-116

    6. Non-iron-induced Disturbances of Erythropoiesis

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 117-131

  5. Laboratory

    1. Methods of Determination

      • Manfred Wick, Wulf Pinggera, Paul Lehmann
      Pages 132-175

  6. Back Matter

    Pages 176-196
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Keywords

About this book

Iron is essential for most forms of life, including humans. On the other hand, iron is also potentially toxic. Therefore, the control of iron metabolism and maintenance of iron hemostasis is an crucial part of many aspects of human health and disease. Iron deficiency anemia is one of the most common diseases worldwide, but there are also anemias associated with chronic diseases, and other acquired or hereditary defects. Understanding the control of iron metabolism is furthermore important for understanding diseases of iron overload, like hemochromatosis. This booklet is designed for physicians, clinical lab personnel and medical students. It gives an overview about the principles of regulation of iron metabolism and erythropoiesis. In addition, the various disturbances of iron metabolism and the associated clinical findings are described. Special focus lies on the differential diagnosis of the disorders, and the approaches of therapy. Finally, a comprehensive schedule of tests is included available for the determination of iron metabolism-related parameters in serum/plasma and blood, with indication of methodologies applied and reference ranges.

Authors and Affiliations

  • Institute of Clinical Chemistry, Klinikum Grosshadern, University of Munich, Germany

    Manfred Wick

  • Maria Taferl, Austria

    Wulf Pinggera

  • Mainz, Germany

    Paul Lehmann

Bibliographic Information

  • Book Title: Clinical Aspects and Laboratory. Iron Metabolism, Anemias

  • Book Subtitle: Concepts in the anemias of malignancies and renal and rheumatoid diseases

  • Authors: Manfred Wick, Wulf Pinggera, Paul Lehmann

  • DOI: https://doi.org/10.1007/978-3-7091-0087-5

  • Publisher: Springer Vienna

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Vienna 2011

  • Softcover ISBN: 978-3-7091-0086-8Published: 23 December 2010

  • eBook ISBN: 978-3-7091-0087-5Published: 01 February 2012

  • Edition Number: 6

  • Number of Pages: X, 198

  • Number of Illustrations: 57 b/w illustrations

  • Additional Information: 4th edition published with the title " Iron Metabolism, Anemias. Diagnosis and Therapy"

  • Topics: Hematology, Metabolic Diseases, Nephrology, Rheumatology

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