COPD

1. Front Matter

   Pages i-viii

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2. Overview

   1. Front Matter

      Pages 1-1

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   2. Definition and Epidemiology of COPD

      • Young Sam Kim

      Pages 3-7

   3. Risk Factors: Factors That Influence Disease Development and Progression

      • Ji Ye Jung

      Pages 9-15

   4. Pathology of Chronic Obstructive Pulmonary Diseases

      • Rubin M. Tuder

      Pages 17-33

   5. Pathogenesis of COPD

      • Ji-Hyun Lee

      Pages 35-54

3. Assessment

   1. Front Matter

      Pages 55-55

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   2. Pathophysiology of COPD

      • Eun Kyung Kim

      Pages 57-63

   3. Diagnosis and Assessment of COPD

      • Yong Bum Park

      Pages 65-74

   4. Symptomatic Assessment of COPD

      • Paul W. Jones

      Pages 75-86

   5. Imaging of COPD

      • Sang Min Lee, Song Soo Kim, Hye Jeon Hwang, Joon Beom Seo

      Pages 87-127

   6. Biomarkers of COPD

      • Ho Il Yoon

      Pages 129-143

4. Heterogeneity

   1. Front Matter

      Pages 145-145

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   2. Phenotypes of COPD

      • Jamie Sheth, MeiLan Han

      Pages 147-168

   3. Genetics of COPD

      • Woo Jin Kim

      Pages 169-177

   4. Imaging Heterogeneity of COPD

      • Sang Min Lee, Joon Beom Seo

      Pages 179-187

   5. Asthma-COPD Overlap Syndrome

      • Chin Kook Rhee

      Pages 189-193

   6. The Spectrum of Pulmonary Disease in COPD

      • Norbert F. Voelkel, Shiro Mizuno, Carlyne D. Cool

      Pages 195-207

5. Management

   1. Front Matter

      Pages 209-209

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   2. Prevention of COPD

      • HyoungKyu Yoon

      Pages 211-217

This book explains how analysis of the heterogeneity of chronic obstructive pulmonary disease (COPD) enhances understanding of the condition and leads to improved, personalized treatment. State of the art knowledge is presented on a range of issues related to the heterogeneity of COPD, such as phenotypes (clinical, physiologic, radiologic, etc.), genotypes, and the tools to be used for dissecting heterogeneity (CT, MRI, biomarkers, etc.). Especially modern radiologic imaging holds promise in this context, and its role is described in detail with the aid of numerous illustrations. The implications of the heterogeneity for personalized treatment are clearly identified, with description of an appropriate tailored treatment strategy for each subgroup of patients. Information is provided on both current and emerging strategies, including bronchoscopic lung volume reduction and approaches to the management of pulmonary hypertension and comorbidities. This book will be a great asset in clinical practice and research for all who have an interest in COPD, a leading cause of morbidity and mortality worldwide.

• ACOS
• Assessment Tools
• Heterogeneity of COPD
• Personalized Treatment
• Pulmonary Hypertension
• Diagnostic Radiology

• Department of Pulmonary and Critical, Asan Medical Center University of Ulsan College of Medicine, Seoul, Korea (Republic of)

  Sang-Do Lee

Sang-Do Lee is Professor in Pulmonary and Critical Care Medicine at University of Ulsan College of Medicine. He is the President of Asan Medical Center, Seoul and Director at Clinical Research Center for Chronic Obstructive Airway Diseases.

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