Behavioral Neurobiology of Stress-related Disorders

1. Front Matter

   Pages i-x

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2. Neuronal-Glial Mechanisms of Exercise-Evoked Stress Robustness

   • Monika Fleshner, Benjamin N. Greenwood, Raz Yirmiya

   Pages 1-12

3. The Interface of Stress and the HPA Axis in Behavioural Phenotypes of Mental Illness

   • David Baumeister, Stafford L. Lightman, Carmine M. Pariante

   Pages 13-24

4. Adult Hippocampal Neurogenesis in Depression: Behavioral Implications and Regulation by the Stress System

   • Christoph Anacker

   Pages 25-43

5. Impact of Stress on Prefrontal Glutamatergic, Monoaminergic and Cannabinoid Systems

   • M. Danet Lapiz-Bluhm

   Pages 45-66

6. Interaction of Stress, Corticotropin-Releasing Factor, Arginine Vasopressin and Behaviour

   • Eléonore Beurel, Charles B. Nemeroff

   Pages 67-80

7. Long-lasting Consequences of Early Life Stress on Brain Structure, Emotion and Cognition

   • Harm J. Krugers, Marian Joëls

   Pages 81-92

8. Mechanisms Linking In Utero Stress to Altered Offspring Behaviour

   • Theresia H. Mina, Rebecca M. Reynolds

   Pages 93-122

9. Does Stress Elicit Depression? Evidence From Clinical and Preclinical Studies

   • Helle M. Sickmann, Yan Li, Arne Mørk, Connie Sanchez, Maria Gulinello

   Pages 123-159

10. Neurobehavioral Mechanisms of Traumatic Stress in Post-traumatic Stress Disorder

    • M. Danet Lapiz-Bluhm, Alan L. Peterson

    Pages 161-190

11. Investigation of Cortisol Levels in Patients with Anxiety Disorders: A Structured Review

    • Hesham Yousry Elnazer, David S. Baldwin

    Pages 191-216

12. Stress, Schizophrenia and Bipolar Disorder

    • Melissa J. Green, Leah Girshkin, Nina Teroganova, Yann Quidé

    Pages 217-235

13. Stress, Substance Abuse, and Addiction

    • Tiffany M. Duffing, Stefanie G. Greiner, Charles W. Mathias, Donald M. Dougherty

    Pages 237-263

14. Role of Stress, Depression, and Aging in Cognitive Decline and Alzheimer’s Disease

    • Mak Adam Daulatzai

    Pages 265-296

15. Stress and Psychological Resiliency

    • Alan L. Peterson, Tabatha H. Blount, Donald D. McGeary

    Pages 297-312

16. Back Matter

    Pages 313-315

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Stress is such an over-used word that it is at time difficult to define its core features. When is an environment stressful? What does a stressful environment do to the brain and to the body? What are the biological mechanisms by which a stressor affects us? How does stress contributes to the onset and the progression of mental disorders? How do the effects of stress change over the life-time of an individual? These are just some of the overarching questions addressed by this book, thanks to the contribution of some of the world leading experts on the neurobiology of stress at the pre-clinical and clinical levels. Topics include current advances on the neurobiology of stress on various neurobiological systems such as immune, hypothalamic-pituitary-adrenal (HPA) axis, neurogenesis and neuroplasticity, neurotransmitter (glutamate, noradrenaline, dopamine, serotonin and endocannabinoid), neuropeptides, cognition and emotional processing as well as in utero and early postnatal effects. The clinical chapters deal with the relationship of stress and mental disorders such as depression, posttraumatic stress disorder (PTSD), anxiety disorders, schizophrenia, bipolar disorder, substance abuse and addiction, dementia and age-related cognitive decline as well as resilience to stress. Thus, this book brings together some of the most updated and authoritative views on the effects of stress of brain and behavior.

• PTSD
• neurobiology of stress
• neuroplasticity
• psychiatric disorders
• stress disorders

• Department of Psychological Medicine, Institute of Psychiatry Kings College London, London, United Kingdom

  Carmine M. Pariante

• Family and Community Health Systems, University of Texas Health Science Center at San Antonio, San Antonio, USA

  M. Danet Lapiz-Bluhm

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