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Autonomic Innervation of the Heart

Role of Molecular Imaging

  • Book
  • © 2015

Overview

Editors:
  1. Riemer H.J.A. Slart

    1. Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands

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  2. René A. Tio

    1. Thorax center Cardiology, University Medical Center Groningen, Groningen, The Netherlands

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  3. Philip H. Elsinga

    1. Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands

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  4. Markus Schwaiger

    1. Nuklearmedizinische Klinik, Klinikum Rechts der Isar Technische Universität München, München, Germany

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  • Reviews in detail the value of SPECT-CT and PET-CT in the imaging of cardiac innervation
  • Details the role of imaging in a range of conditions and diseases
  • Includes important background on pathophysiology, tracers, radiopharmaceutical production, and kinetic modeling software

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. The Autonomic Nervous System of the Heart

    • Irma Battipaglia, Gaetano A. Lanza
    Pages 1-12

  3. Electrophysiology and Pathophysiology of the Autonomic Nervous System of the Heart

    • Carlo de Asmundis, Guy Van Camp, Pedro Brugada
    Pages 13-60

  4. Development of Heart Failure and the Role of the Autonomic Nervous System of the Heart

    • S. Pardaens, J. De Sutter
    Pages 61-75

  5. Role of the Autonomic Nervous System in Ventricular Arrhythmias During Acute Myocardial Ischemia and Infarction

    • Richard L. Verrier, Alex Y. Tan
    Pages 77-85

  6. Tracers for Sympathetic Cardiac Neurotransmission Imaging

    • James T. Thackeray, Jean N. DaSilva, Philip H. Elsinga
    Pages 87-109

  7. Imaging the Parasympathetic Cardiac Innervation with PET

    • Dominique Le Guludec, Jacques Delforge, Frédéric Dollé
    Pages 111-135

  8. Tracer Application in Cardiovascular Imaging: A Triple Jump

    • F. Michelle de Roo, Koen Hilgerink, Jos G. W. Kosterink, Gert Luurtsema, Herman J. Woerdenbag, Hendrikus H. Boersma
    Pages 137-159

  9. General Principles of PET/CT and Autonomic Innervation of the Heart Including Kinetics and Software

    • Stephan G. Nekolla, Christoph Rischpler
    Pages 161-185

  10. General Principles of [123I]-MIBG Scintigraphy for the Assessment of the Cardiac Sympathetic Activity: From Planar to SPECT

    • Hein J. Verberne, Arthur J. H. A. Scholte
    Pages 187-199

  11. Preclinical Evaluations of Cardiac Sympathetic Innervation Radiotracers

    • David M. Raffel
    Pages 201-234

  12. PET Imaging of Myocardial β-Adrenoceptors

    • Riemer H. J. A. Slart, Peter van der Meer, René A. Tio, Dirk J. van Veldhuisen, Philip H. Elsinga
    Pages 235-253

  13. Autonomic PET-CT Imaging in Heart Failure

    • Juhani Knuuti
    Pages 255-262

  14. Conventional Radionuclide Imaging of Autonomic Function in Heart Failure

    • Arnold F. Jacobson, Jagat Narula
    Pages 263-288

  15. Autonomic Imaging in Myocardial Ischemia

    • Ichiro Matsunari, Junichi Taki
    Pages 289-307

  16. Imaging the Cardiac Automatic Nervous System in Diabetes Mellitus

    • Arthur J. H. A. Scholte, Hein J. Verberne
    Pages 309-320

  17. Imaging of the Autonomic Nervous System in Cardiac Amyloidosis

    • Walter Noordzij, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart, Bouke P. C. Hazenberg
    Pages 321-335

  18. Autonomic Imaging in Heart Transplantation

    • Frank M. Bengel
    Pages 337-346

  19. Autonomic Imaging in Ventricular Arrhythmias

    • Alexis Vrachimis, Michael Schäfers, Lars Stegger, Christian Wenning
    Pages 347-365

  20. Imaging Sympathetic Innervation of the Heart: Therapeutic Strategies SPECT/CT and PET/CT

    • Erick Alexanderson, Albert Flotats, Luis Eduardo Juárez-Orozco
    Pages 367-385
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Keywords

About this book

This book explains in detail the potential value of the hybrid modalities, SPECT-CT and PET-CT, in the imaging of cardiac innervation in a wide range of conditions and diseases, including ischemic heart disease, diabetes mellitus, heart failure, amyloidosis, heart transplantation, and ventricular arrhythmias. Imaging of the brain-heart axis in neurodegenerative disease and stress and of cardiotoxicity is also discussed. The roles of the various available tracers are fully considered, and individual chapters address radiopharmaceutical development under GMP, imaging physics, and kinetic modeling software. Highly relevant background information is included on the autonomic nervous system of the heart and its pathophysiology, and in addition future perspectives are discussed.

Awareness of the importance of autonomic innervation of the heart for the optimal management of cardiac patients is growing, and there is an evident need for objective measurement techniques or imaging modalities. In this context, Autonomic Innervation of the Heart will be of wide interest to clinicians, researchers, and industry.

Reviews

“This book represents a qualified, extensive and updated book on the role of molecular imaging of the autonomic innervations of the heart, which can generate the interest of all the nuclear physicians, residents, cardiologists, neurologists, and basic scientists, and of all others who want to be introduced to a very intriguing new field of clinical applications, in which other knowledge and methodological improvements are needed to support a wider diffusion in clinical practice.” (Valentina Piscopo and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, March, 2016)

Editors and Affiliations

  • Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands

    Riemer H.J.A. Slart, Philip H. Elsinga

  • Thorax center Cardiology, University Medical Center Groningen, Groningen, The Netherlands

    René A. Tio

  • Nuklearmedizinische Klinik, Klinikum Rechts der Isar Technische Universität München, München, Germany

    Markus Schwaiger

Bibliographic Information

  • Book Title: Autonomic Innervation of the Heart

  • Book Subtitle: Role of Molecular Imaging

  • Editors: Riemer H.J.A. Slart, René A. Tio, Philip H. Elsinga, Markus Schwaiger

  • DOI: https://doi.org/10.1007/978-3-662-45074-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2015

  • Hardcover ISBN: 978-3-662-45073-4Published: 09 March 2015

  • Softcover ISBN: 978-3-662-51073-5Published: 06 October 2016

  • eBook ISBN: 978-3-662-45074-1Published: 30 January 2015

  • Edition Number: 1

  • Number of Pages: XVII, 465

  • Number of Illustrations: 36 b/w illustrations, 64 illustrations in colour

  • Topics: Diagnostic Radiology, Nuclear Medicine, Cardiology

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