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  • © 2015

Development and Reproduction in Humans and Animal Model Species

  • Optimal introduction for beginners and coherent overview for advanced students
  • Clearly demonstrates basic principles through didactically designed four-color illustrations
  • Offers comprehensive glossary

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xi
  2. Development and Reproduction: An Introduction

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 1-19
  3. Stages and Principles of Animal Development: Terms of Developmental Biology

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 21-37
  4. Model Organisms in Developmental Biology I: Invertebrates

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 59-121
  5. Development of Important Model Species II: Vertebrates

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 123-167
  6. The Human

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 169-213
  7. In Preparation for New Life I: Sex Determination and Sexual Development

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 215-240
  8. Specification of Body Axes and Localized Fate Allotment by External and Maternal Cues

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 259-270
  9. Positional Information, Embryonic Induction and Pattern Formation by Cell-Cell-Communication

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 271-322
  10. Controlling Signals, Signal Propagation and Signal Transduction

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 323-351
  11. Development and Genes

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 353-413
  12. Application-Oriented Experiments with Early Vertebrate Embryos: Cloning, Transgenic Animals

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 415-432
  13. Morphogenesis: Shaping by Active Cell Movement, Differential Cell Adhesion and Cell Death

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 433-442
  14. Long Distance Wanderers and the Various Fates of the Neural Crest Cells

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 443-453
  15. The Nervous System and Central Sensory Organs

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 455-498
  16. Heart and Blood Vessels

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 499-516
  17. Stem Cells, Regeneration, Regenerative Medicine

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 517-557
  18. Growth Control and Cancer

    • Werner A. Mueller, Monika Hassel, Maura Grealy
    Pages 559-569

About this book

This book describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development; genes controlling development and their contemporary molecular-analysis methods; production of clones and transgenic animals; development of the nervous and circulatory systems; regenerative medicine and ageing. Finally the evolution of developmental toolkits and novelties is discussed including the genetic basis of the enlargement of the human forebrain.

Separate boxes are devoted to controversial questions such as the benefits and problems of prenatal diagnostics or the construction of ancient body plans.

Reviews

“This English language textbook is a translation and updating of the fifth German edition. Production is excellent with a readable text, copious figures, and a detailed index. … the volume does contains 50 pages of references organized by chapter topics. … Much of the material is on human development … with other animals used as model species.” (Brian K. Hall, The Quarterly Review of Biology, Vol. 91 (1), March, 2016)

Authors and Affiliations

  • Centre of Organismal Studies, University of Heidelberg, Heidelberg, Germany

    Werner A. Mueller

  • Spezielle Zoologie, Universität Marburg FB Biologie, Marburg, Germany

    Monika Hassel

  • Pharmacology and Therapeutics, National University of Ireland Galway, Galway, Ireland

    Maura Grealy

About the authors

Werner A. Mueller (Müller) was head of the Zoological Institute of the University of Heidelberg, Germany, for 30 years. He is also author of a textbook on Animal and Human Physiology. He and his group did research on stem cells, pattern formation, signalling molecules including neuropeptides and on settlement and metamorphosis of marine organisms. Monika Hassel is leader of the department on Morphology and Evolution of Invertebrates at the University of Marburg, Germany. She and her group use invertebrate model systems (Hydra, Platynereis) to elucidate the role of fibroblast growth factor receptors in the emergence of body plans and the development of boundaries. Maura Grealy is lecturer at the department of Pharmacology and Therapeutics at the National University in Galway, Ireland. She and her group use the zebrafish as model organism to study the onset of transcription in embryogenesis, heart development and the role of signalling cell adhesion molecules.

Bibliographic Information

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access