The Meaning of Nucleocytoplasmic Transport

1. Front Matter

   Pages i-viii

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2. Perspectives in Transport

   • Paul S. Agutter, Philip L. Taylor

   Pages 1-20

3. The Vagaries of Diffusion

   • Paul S. Agutter, Philip L. Taylor

   Pages 21-52

4. Cellular Structures and Nucleocytoplasmic Transport

   • Paul S. Agutter, Philip L. Taylor

   Pages 53-80

5. Events at the Pore-Complex

   • Paul S. Agutter, Philip L. Taylor

   Pages 81-117

6. Events Involving the Nucleoskeleton and Cytoskeleton

   • Paul S. Agutter, Philip L. Taylor

   Pages 119-152

7. Regulation and Pathologies of Nucleocytoplasmic Transport

   • Paul S. Agutter, Philip L. Taylor

   Pages 153-179

8. Evaluation of a Model

   • Paul S. Agutter, Philip L. Taylor

   Pages 181-197

9. Back Matter

   Pages 199-200

   PDF

The means by which proteins and RNAs are exchanged between cytoplasm and nucleus have interested cell biologists for many years, and the field has seen a number of exciting recent advances. Much has been learned about the intricate architecture of the nuclear pore-complex, the mechanisms by which transport substrates are sorted, and the supply of energy for exchange processes. This book attempts a general review of the growing body of knowledge. However, the authors challenge the presumptions implicit in some interpretations of the evidence, re-examining the concept of "transport" within cells, and suggesting that lessons learned from nucleocytoplasmic transport studies can elucidate wider aspects of cell biology.

• biology
• cell
• cell biology
• protein
• proteins

• Napier University, Edinburgh, Scotland

  Paul S. Agutter

• Edinburgh, Scotland

  Philip L. Taylor

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