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Sphingolipid-Mediated Signal Transduction

  • Book
  • © 1997

Overview

Authors:
  1. Yusuf A. Hannun

    1. Departments of Medicine and Cell Biology, Duke University Medical Center, Durham, USA

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Part of the book series: Molecular Biology Intelligence Unit (MBIU)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Introduction and Overview

    • Yusuf A. Hannun
    Pages 1-18

  3. Ceramide: A Stress Response Mediator Involved in Growth Suppression

    • Ghassan Dbaibo, Yusuf A. Hannun
    Pages 19-34

  4. Ceramide and Inflammation

    • Leslie R. Ballou
    Pages 35-51

  5. A Role for Ceramide in Meiosis

    • Jay C. Strum, Katherine I. Swenson, Robert M. Bell
    Pages 53-60

  6. Ceramide, Aging and Cellular Senescence

    • Joanna Y. Lee, Lina M. Obeid
    Pages 61-75

  7. Ceramide, a Mediator of Cytosine Arabinoside Induced Apoptosis

    • Susan P. Whitman, Larry W. Daniel
    Pages 77-90

  8. The Use of Cerebroside Synthase Inhibitors as Probes for Assessing the Metabolism and Function of Sphingolipids

    • James A. Shayman, Norman S. Radin
    Pages 91-101

  9. Role of Sphingolipids in Regulating the Phospholipase D Pathway and Cell Division

    • Antonio Gómez-Muñoz, Abdelkarim Abousalham, Yutaka Kikuchi, David W. Waggoner, David N. Brindley
    Pages 103-120

  10. Sphingosine-1-Phosphate: Member of a New Class of Lipid Second Messengers

    • Sarah Spiegel, Olivier Cuvillier, Elena Fuior, Sheldon Milstien
    Pages 121-135

  11. Functional Roles of Glycosphingolipids and Sphingolipids in Signal Transduction

    • Sen-itiroh Hakomori
    Pages 137-158

  12. Ceramide Synthase and Ceramidases in the Regulation of Sphingoid Base Metabolism

    • Mariana Nikolova-Karakashian, Teresa R. Vales, Elaine Wang, David S. Menaldino, Christopher Alexander, Jane Goh et al.
    Pages 159-172

  13. Ceramidase and Signal Transduction

    • Charles P. Mckay
    Pages 173-181

  14. Back Matter

    Pages 183-188
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Keywords

About this book

Lipid-derived molecules are increasingly appreciated as key regulators of cell responses and signal transduction. Sphingolipid-derived bioactive molecules are emerging as critical regulators of some of the most exciting and, until recently, poorly-understood areas of biology such as growth suppression, programmed cell death and tumor invasion. Written by leading investigators in these areas of study, this book presents a thorough, current and accessible review of how sphingolipids function to regulate these important activities.

Authors and Affiliations

  • Departments of Medicine and Cell Biology, Duke University Medical Center, Durham, USA

    Yusuf A. Hannun

Bibliographic Information

  • Book Title: Sphingolipid-Mediated Signal Transduction

  • Authors: Yusuf A. Hannun

  • Series Title: Molecular Biology Intelligence Unit

  • DOI: https://doi.org/10.1007/978-3-662-22425-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1997

  • Softcover ISBN: 978-3-662-22427-4Published: 13 November 2013

  • eBook ISBN: 978-3-662-22425-0Published: 29 June 2013

  • Series ISSN: 1431-0414

  • Edition Number: 1

  • Number of Pages: XVII, 188

  • Number of Illustrations: 8 b/w illustrations

  • Additional Information: Jointly published with R.G. Landes, Biomedical Publishers, Austin, USA

  • Topics: Cell Biology, Biochemistry, general

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