Molecular and Cellular Endocrinology of the Testis

1. Front Matter

   Pages I-XIV

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2. Hormonal Receptors in the Genital Tract

   • A. Chauchereau, A. Mantel, K. Delabre, M. Misrahi, P. Lescop, M. Perrot-Applanat et al.

   Pages 1-13

3. Transplantation of Male and Female Germ and Somatic Cells

   • R. G. Gosden

   Pages 15-35

4. Proliferation and Differentiation of Testicular Interstitial Cells: Aspects of Leydig Cell Development in the (Pre)Pubertal and Adult Testis

   • K. J. Teerds, M. B. Veldhuizen-Tsoerkan, F. F. G. Rommerts, D. G. de Rooij, J. H. Dorrington

   Pages 37-65

5. Regulation of the Acute Production of Steroids in Steroidogenic Cells

   • D. M. Stocco, B. J. Clark

   Pages 67-98

6. Extracellular Matrix Elements, Cell Adhesion Molecules, and Signal Transduction in the Control of Sertoli Cell Function

   • M. Dym

   Pages 99-114

7. Interactions Between Androgens, Sertoli Cells and Germ Cells in the Control of Spermatogenesis

   • R. M. Sharpe, C. McKinnell, T. McLaren, M. Millar, T. P. West, S. Maguire et al.

   Pages 115-142

8. Cell Cycle Checkpoints in Male and Female Germ Cells

   • D. F. Albertini

   Pages 143-152

9. Signal Transduction in Mammalian Spermatozoa

   • G. S. Kopf, P. Kalab, P. Leclerc, X. P. Ning, D. Pan, P. Visconti

   Pages 153-183

10. Diversity and Regulation of cAMP-Dependent Protein Kinases

    • K. Taskén, B. S. Skålhegg, K. A. Taskén, R. Solberg, F. O. Levy, T. Lea et al.

    Pages 185-217

11. The Nuclear Response to cAMP During Spermatogenesis: The Key Role of Transcription Factor CREM

    • P. Sassone-Corsi

    Pages 219-252

12. Transgenic Animals and the Study of Gonadal Function

    • M. M. Matzuk

    Pages 253-271

13. Clinical Relevance and Irrelevance of Molecular and Cellular Research on the Testis

    • E. Nieschlag

    Pages 273-292

14. Back Matter

    Pages 293-298

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The European Workshops on Molecular and Cellular Endocrinology of the Testis have become by now a well-established tradition. Thanks to their special format, the quality of the main lectures and miniposters, and the vivid discussions, they enjoy the ever-increasing interest and active participation of all European scientists working in the field. Moreover, since the very beginning they have attracted investigators from all over the world. The most recent "Testis Workshop" was held in De Panne, Belgium, from 27-3\ March, 1994. As always, the frame­ work of the workshop was provided by a series of lectures delivered by a panel of internationally recognized authorities. These lectures are ga­ thered in the present volume of the Ernst Schering Foundation Work­ shop series. Together with the Miniposter book they constitute an excel­ lent written account of the Proceedings of the 8th European Testis Workshop. The testis undoubtedly represents one of the most complex and in­ triguing tissues in the body. Both its endocrine function, the secretion of male sex hormones, and its exocrine role, the production of mature spermatozoa, continue to raise startling questions to clinicians, physi­ ologists, endocrinologists, and scientists involved in fundamental re­ search. Few organs maintain and support a differentiation process as complicated as spermatogenesis; few tissues continually display both mitotic and meiotic cell cyles in such a stringently controlled fashion or a comparable need for coordinated endocrine and local control.

• Cell-biology
• Endocrinology
• Signal-transduction
• cell
• cell differentiation
• regulation
• reproduction
• signal transduction
• spermatogenesis
• steroid
• testis

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