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Tacrolimus Ointment

A Topical Immunomodulator for Atopic Dermatitis

  • Book
  • © 2004

Overview

Editors:
  1. Thomas Ruzicka

    1. Universitätsklinikum Düsseldorf Hautklinik, Heinrich-Heine-Universität, Düsseldorf, Germany

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  2. Sakari Reitamo

    1. Hospital for Skin and Allergic Diseases, Department of Dermatology, Helsinki University Central Hospital, Helsinki, Finland

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (13 chapters)

  1. Front Matter

    Pages I-XX
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  2. Atopic Dermatitis

    1. Front Matter

      Pages 1-1
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    2. Epidemiology of Atopic Dermatitis

      • T. L. Diepgen
      Pages 3-21

    3. The Pathogenesis of the Atopic Eczema/Dermatitis Syndrome

      • N. Novak, T. Bieber
      Pages 23-45

    4. Detecting, Diagnosing and Grading Atopic Dermatitis

      • J. M. Hanifin
      Pages 47-61

    5. Current Treatment of Atopic Dermatitis

      • J. D. Bos
      Pages 63-77

  3. Development of Tacrolimus Ointment

    1. Front Matter

      Pages 80-80
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    2. Development of Tacrolimus Ointment

      • T. Goto, H. Nakagawa
      Pages 81-98

    3. Pharmacokinetics of Tacrolimus Ointment: Clinical Relevance

      • N. A. Undre
      Pages 99-110

    4. Tacrolimus as an Immunomodulator

      • T. Assmann, B. Homey, T. Ruzicka
      Pages 111-126

  4. Clinical Experience with Tacrolimus Ointment in Atopic Dermatitis

    1. Front Matter

      Pages 128-128
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    2. Clinical Experience in Adults

      • S. Reitamo
      Pages 129-160

    3. Clinical Experience in Children

      • Y. de Prost
      Pages 161-183

    4. The Role of Tacrolimus Ointment in Atopic Dermatitis

      • S. Reitamo
      Pages 185-211

    5. Other Potential Dermatological Indications for Tacrolimus

      • T. Assmann, T. Ruzicka
      Pages 213-233

  5. Social Impact of Atopic Dermatitis

    1. Front Matter

      Pages 235-235
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    2. Quality of Life Measurements in Atopic Dermatitis

      • A. Y. Finlay, W. H. C. Burgdorf
      Pages 237-254

    3. Pharmacoeconomics in Atopic Dermatitis

      • M. Augustin
      Pages 255-270

  6. Back Matter

    Pages 271-279
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Keywords

About this book

Therapeutic breakthroughs in medicine are usually accompanied by a wealth of data. Often they result in a change of disease treatment paradigms. Tacrolimus ointment is the first in the new class of steroid-free Topical Immunomodulators (TIMs), and as such represents the first true breakthrough since the introduction of topical steroids more than 50 years ago for the treatment of T-cell mediated inflammatory skin diseases such as atopic dermatitis. This book gives an easy-to-read overview of the discovery and the development of Tacrolimus ointment for the treatment of atopic dermatitis. Summarising the largest clinical trial program ever conducted in dermatology for a new treatment with more than 13000 patients, it offers a detailed insight into the efficacy and safety profile of Tacrolimus ointment. Based on this large body of data and extensive personal experience, the authors offer practical and hands-on guidance for the physician as to when and how to use Tacrolimus ointment in daily practice.

Editors and Affiliations

  • Universitätsklinikum Düsseldorf Hautklinik, Heinrich-Heine-Universität, Düsseldorf, Germany

    Thomas Ruzicka

  • Hospital for Skin and Allergic Diseases, Department of Dermatology, Helsinki University Central Hospital, Helsinki, Finland

    Sakari Reitamo

Bibliographic Information

  • Book Title: Tacrolimus Ointment

  • Book Subtitle: A Topical Immunomodulator for Atopic Dermatitis

  • Editors: Thomas Ruzicka, Sakari Reitamo

  • DOI: https://doi.org/10.1007/978-3-662-10209-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2004

  • Softcover ISBN: 978-3-662-10211-4Published: 23 August 2014

  • eBook ISBN: 978-3-662-10209-1Published: 17 April 2013

  • Edition Number: 1

  • Number of Pages: XX, 279

  • Number of Illustrations: 1 b/w illustrations, 1066 illustrations in colour

  • Topics: Dermatology

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