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  • Textbook
  • © 2004

Computation in Living Cells

Gene Assembly in Ciliates

  • Makes underlying biology very accessible to computer science and mathematics students
  • First book/monograph on Computation in Living Cells
  • Includes supplementary material: sn.pub/extras

Part of the book series: Natural Computing Series (NCS)

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Table of contents (16 chapters)

  1. Front Matter

    Pages I-XIV
  2. Biological Background

    1. Front Matter

      Pages 1-1
    2. An Overview of the Cell

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 3-21
    3. Ciliates

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 23-35
    4. Molecular Operations for Gene Assembly

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 37-43
  3. Formal Modelling of Gene Assembly

    1. Front Matter

      Pages 45-45
    2. Model Forming

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 47-56
    3. Mathematical Preliminaries

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 57-65
    4. MDS Arrangements and MDS Descriptors

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 67-73
    5. MDS Descriptor Pointer Reduction System

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 75-81
    6. Legal Strings

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 83-90
    7. String Pointer Reduction System

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 91-98
    8. Overlap Graphs

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 99-108
    9. Graph Pointer Reduction System

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 109-117
  4. Properties of Gene Assembly

    1. Front Matter

      Pages 119-119
    2. Invariants

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 121-129
    3. Patterns of Subsets of Rules

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 131-149
    4. Gene Assembly Through Cyclic Graph Decomposition

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 151-175
  5. Epilogue

    1. Front Matter

      Pages 177-177
    2. Intermolecular Model

      • Andrzej Ehrenfeucht, Tero Harju, Ion Petre, David M. Prescott, Grzegorz Rozenberg
      Pages 179-185

About this book

Natural Computing is concerned with computation that is taking place in Nature. The investigation of computations in living cells is one of the central and fastest growing areas of research in this field. Gene assembly in ciliates (unicellular organisms) is a splendid example of such computations, and it is fascinating from both the biological and the computational viewpoints. As a matter of fact, both biology and the science of computation have benefited from the interdisciplinary research on the computational nature of gene assembly – this work has helped to clarify important biological aspects of gene assembly, yielded novel insights into the nature of computation, and broadened our understanding of what computation is about.

This monograph gives an accessible account of both the biology and the formal analysis of the gene assembly process. It can be used as a textbook for either graduate courses or seminars.

Authors and Affiliations

  • Department of Computer Science, University of Colorado, Boulder, USA

    Andrzej Ehrenfeucht

  • Department of Mathematics, University of Turku, Turku, Finland

    Tero Harju

  • Department of Computer Science, Åbo Akademi University, Turku, Finland

    Ion Petre

  • Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, USA

    David M. Prescott

  • Leiden Institute for Advanced Computer Science, Leiden University, Leiden, The Netherlands

    Grzegorz Rozenberg

About the authors

Prof. Rozenberg is multiple Springer author/editor of, e.g., the LNCS series Advances in Petri Nets, of ICALP proceedings, of  "DNA Computing – New Computing Paradigms" by George Paun, Grzegorz Rozenberg, Arto Salomaa, of the "Handbook of Formal Languages" edited by Grzegorz Rozenberg, Arto Salomaa (3 volumes). Rozenberg is also founding editor of the EATCS Texts and Monographs Series and the Natural Computing Series.

Bibliographic Information

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access