Overview
- Authors:
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Marek Michalak
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MRC Group in Molecular Biology of Membranes, Department of Biochemistry, University of Alberta, Edmonton, Canada
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Table of contents (12 chapters)
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Front Matter
Pages i-xiii
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- Marek Michalak, Christi Andrin
Pages 1-10
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- Shairaz Baksh, Marek Michalak
Pages 11-30
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- Frank Parlati, Richard Hemming, Wei-Jia Ou, John J. M. Bergeron, David Y. Thomas
Pages 43-57
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- Chintamani D. Atreya, Gregory P. Pogue, Nishi K. Singh, Hira L. Nakhasi
Pages 89-115
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- Richard D. Sontheimer, Tho Q. Nguyen, Shih-Tsung Cheng, Tsu-San Lieu, J. Donald Capra
Pages 117-139
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- R. Chris Bleackley, Michael J. Pinkoski, Eric A. Atkinson
Pages 141-153
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- David J. Pinsky, Keisuke Kuwabara, Ann Marie Schmidt, Charles A. Lawson, Claude Benedict, Johan Broekman et al.
Pages 155-168
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- Deborah C. Jaworski, Glen R. Needham
Pages 169-180
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- Victor B. Hatcher, Christina Samathanam
Pages 181-200
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Back Matter
Pages 201-213
About this book
This book is about calreticulin, a multifunctional calcium binding protein first discovered over 20 years ago. The protein has been described in various locations: endoplasmic reticulum, nuclear envelope, cytoplasmic granules, nucleus, cell surface and even secreted into the blood stream. This volume outlines the newly discovered functions for calreticulin including its control of calcium homeostasis, modulation of steroid-sensitive gene expression, control of viral RNA replication, modulation of nuclear transport, role in T lymphocyte activation and cytotoxic killing, chaperone function, control of adhesion-dependent signaling via integrins, possible role in the biology of ticks, in the pathology of autoimmune diseases and in blood function.
Authors and Affiliations
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MRC Group in Molecular Biology of Membranes, Department of Biochemistry, University of Alberta, Edmonton, Canada
Marek Michalak
