Skip to main content
SpringerLink
Log in

Therapeutic Vaccination Strategies

  • Conference proceedings
  • © 2000

Overview

Editors:
  1. P. Walden

    1. Department of Dermatology and Allergy, Medical Faculty Charité, Humboldt University, Berlin, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. W. Sterry

    1. Department of Dermatology and Allergy, Medical Faculty Charité, Humboldt University, Berlin, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. H. Hennekes

    1. Experimental Dermatology, Schering AG, Berlin, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 30)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (12 papers)

  1. Front Matter

    Pages I-XV
    Download chapter PDF

  2. Vaccination Therapy for Malignant Disease: The Clinical Perspective

    • W. Sterry
    Pages 1-6

  3. Tumor Antigens

    • P. Walden
    Pages 7-22

  4. Costimulatory Molecules in Vaccine Design

    • J. W. Hodge, J. Schlom
    Pages 23-52

  5. Application of T Cell lmmunotherapy for Human Viral and Malignant Diseases

    • S. R. Riddell, E. H. Warren, D. Lewinsohn, H. Mutimer, M. Topp, L. Cooper et al.
    Pages 53-73

  6. Immune Monitoring in Cancer Immunotherapy

    • P. Romero, M. J. Pittet, D. Valmori, D. E. Speiser, V. Cerundolo, D. Liénard et al.
    Pages 75-97

  7. Retroviral Vectors for Cancer Gene Therapy

    • M. Collins
    Pages 99-104

  8. CpG Oligonucleotides as Immune Adjuvants

    • A. M. Krieg
    Pages 105-118

  9. DNA Vaccination Against Cancer Antigens

    • F. K. Stevenson, D. Zhu, M. B. Spellerberg, J. Rice, C. A. King, A. R. Thompsett et al.
    Pages 119-136

  10. Skin Cancer — Prospects for Novel Therapeutic Approaches

    • G. Stingl
    Pages 137-153

  11. The Hybrid Cell Vaccination Approach to Cancer lmmunotherapy

    • U. Trefzer, G. Herberth, W. Sterry, P. Walden
    Pages 155-166

  12. T Cell Receptor Peptides for the Vaccination Therapy of Multiple Sclerosis

    • S. Brocke
    Pages 167-179

  13. Regulatory Aspects of Cancer Gene Therapy and DNA Vaccination

    • K. Cichutek
    Pages 181-189

  14. Back Matter

    Pages 191-195
    Download chapter PDF
Back to top

Keywords

About this book

The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major contribution of the immune system to the prevention of cancer. And there are many re­ ports of patients suffering from malignant melanoma or other tumors who mount a spontaneous immune response against their tumor cells that results in tumor regression. Based on the recent advances in our understanding of the compo­ nents of our immune system, their interactions and the regulation of immune responses, we are now able to design vaccination strategies that induce or enhance cell-mediated immunity against tumors. A ma­ jor advancement came with the identification and characterization of relevant tumor antigens, which are suitable target structures for anti-tu­ mor immune response. First clinical trials using such vaccine strategies have yielded encouraging results in patients. However, in spite of many reported cases of successful therapy of cancer by vaccination many patients still do not experience relief after such treatments. These initial clinical trials and the accompanying investigations have revealed a number of important results that indicate the direction of future re­ search and development in the field.

Editors and Affiliations

  • Department of Dermatology and Allergy, Medical Faculty Charité, Humboldt University, Berlin, Germany

    P. Walden, W. Sterry

  • Experimental Dermatology, Schering AG, Berlin, Germany

    H. Hennekes

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation