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The Role of Natural Products in Drug Discovery

  • Conference proceedings
  • © 2000

Overview

Editors:
  1. J. Mulzer

    1. Institut für Organische Chemie, Universität Wien, Wien, Austria

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    You can also search for this editor in PubMed   Google Scholar

  2. R. Bohlmann

    1. Preclinical Drug Research, Schering AG, Berlin, Germany

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 32)

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Table of contents (12 papers)

  1. Front Matter

    Pages I-XIII
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  2. Synthesis of Immunomodulatory Marine Natural Products

    • S. J. Danishefsky, M. Inoue, D. Trauner
    Pages 1-24

  3. The Pederin Family of Antitumor Agents: Structures, Synthesis and Biological Activity

    • R. Narquizian, P. J. Kocienski
    Pages 25-56

  4. Biotherapeutic Potential and Synthesis of Okadaic Acid

    • C. J. Forsyth, A. B. Dounay, S. F. Sabes, R. A. Urbanek
    Pages 57-102

  5. Total Synthesis of Marine Natural Products Driven by Novel Structure, Potent Biological Activity, and/or Synthetic Methodology

    • D. Romo, R. M. Rzasa, W. D. Schmitz, J. Yang, S. T. Cohn, L. R. Buchler et al.
    Pages 103-148

  6. Total Synthesis of Antifungal Natural Products

    • A. G. M. Barrett, W. W. Doubleday, T. Gross, D. Hamprecht, J. P. Henschke, R. A. James et al.
    Pages 149-181

  7. Combinatorial Methods to Engineer Small Molecules for Functional Genomics

    • J. A. Ellman
    Pages 183-204

  8. Natural Products in Drug Discovery

    • H. Müller, O. Brackhagen, R. Brunne, T. Henkel, F. Reichel
    Pages 205-216

  9. Tools for Drug Discovery: Natural Product-based Libraries

    • S. Grabley, R. Thiericke, I. Sattler
    Pages 217-252

  10. Genetic Selection as a Tool in Mechanistic Enzymology and Protein Design

    • D. Hilvert
    Pages 253-268

  11. The Biotechnological Exploitation of Medicinal Plants

    • T. M. Kutchan
    Pages 269-285

  12. Multifunctional Asymmetric Catalysis

    • M. Shibasaki
    Pages 287-314

  13. New Directions in Immunopharmacotherapy

    • K. D. Janda
    Pages 315-346

  14. Back Matter

    Pages 347-351
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Keywords

About this book

Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products.
Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.

Editors and Affiliations

  • Institut für Organische Chemie, Universität Wien, Wien, Austria

    J. Mulzer

  • Preclinical Drug Research, Schering AG, Berlin, Germany

    R. Bohlmann

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