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Excitatory Amino Acids

From Genes to Therapy

  • Conference proceedings
  • © 1998

Overview

Editors:
  1. P. H. Seeburg

    1. Department of Molecular Neuroscience, Max Planck Institute for Medical Research, Heidelberg, Germany

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  2. I. Bresink

    1. Research Laboratories of Schering AG, Berlin, Germany

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    You can also search for this editor in PubMed   Google Scholar

  3. L. Turski

    1. Eisai London Research Laboratories, Bernard Katz Building, University College London, London, UK

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Ernst Schering Foundation Symposium Proceedings (SCHERING FOUND, volume 23)

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Table of contents (10 papers)

  1. Front Matter

    Pages I-XII
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  2. Glutamate Receptor Channels, RNA Editing, and Epilepsy

    • P. H. Seeburg, R. Brusa, M. Higuchi, R. Sprengel
    Pages 1-17

  3. Regulation of Glutamate Receptor Gene Expression in Global Ischemia

    • D. E. Pellegrini-Giampietro
    Pages 19-41

  4. Factors Regulating Excitotoxic Neurodegeneration: The Role of Calcium and the Mitochondria

    • R. J. Miller, V. P. Bindokas, D. F. Babcock, J.-P. Lee, J. B. Jordan
    Pages 43-63

  5. Excitotoxicity, Genetics and Neurodegeneration in Amyotrophic Lateral Sclerosis

    • P. J. Shaw
    Pages 65-94

  6. NO-NMDA Receptor Interactions: A Neuromolecular Approach to Novel Therapeutics

    • S. A. Lipton, Y.-B. Choi, N. J. Sucher, H. S.-V. Chen
    Pages 95-108

  7. Glutamate in Neurodegenerative Disorders: Phenotype Resulting from Decreased Expression of AMPA Receptor GIuR-B Subunit mRNA in Rats

    • G. Müller, U. Endermann, I. Bresink, L. Turski
    Pages 109-126

  8. Quantitative Estimation of NMDA Receptor-Mediated Ca2+ Entry in Central Neurons

    • O. Garaschuk, T. Plant, A. Konnerth
    Pages 127-148

  9. Calcium Permeability of Glutamate-Gated Channels in the CNS: Functional Role of the Ca2+-Permeable AMPA Receptor Channels

    • N. Burnashev
    Pages 149-160

  10. Localisation and Surface Expression of the AMPA Receptor Subunit GluR1 Using Green Fluorescent Protein and Anti-Peptide Antibodies

    • A. Doherty, A. Irving, G. L. Collingridge, J. M. Henley
    Pages 161-185

  11. Input- and Output-Specific Segregation of Amino Acid Neurotransmitter Receptors on the Surface of Central Neurones

    • Z. Nusser, R. Shigemoto
    Pages 187-205

  12. Back Matter

    Pages 207-210
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Keywords

About this book

In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration.

Editors and Affiliations

  • Department of Molecular Neuroscience, Max Planck Institute for Medical Research, Heidelberg, Germany

    P. H. Seeburg

  • Research Laboratories of Schering AG, Berlin, Germany

    I. Bresink

  • Eisai London Research Laboratories, Bernard Katz Building, University College London, London, UK

    L. Turski

Bibliographic Information

  • Book Title: Excitatory Amino Acids

  • Book Subtitle: From Genes to Therapy

  • Editors: P. H. Seeburg, I. Bresink, L. Turski

  • Series Title: Ernst Schering Foundation Symposium Proceedings

  • DOI: https://doi.org/10.1007/978-3-662-03596-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1998

  • Softcover ISBN: 978-3-662-03598-6Published: 08 December 2012

  • eBook ISBN: 978-3-662-03596-2Published: 14 March 2013

  • Series ISSN: 0947-6075

  • Edition Number: 1

  • Number of Pages: XII, 210

  • Number of Illustrations: 103 b/w illustrations, 5 illustrations in colour

  • Topics: Molecular Medicine

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