Sex Steroids and Bone

1. Front Matter

   Pages I-XII

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2. View of a Clinician: Sex Steroids and Osteoporosis

   • Juliet E. Compston

   Pages 1-18

3. The Anabolic Action of Estrogen on Rat Bone

   • Tim J. Chambers, Jade Wei Mun Chow, Jennifer M. Lean, Jonathan H. Tobias

   Pages 19-28

4. Progesterone and Its Role in Bone Remodelling

   • Jerilynn C. Prior

   Pages 29-56

5. The Effect of Sex Steroids on Calciotropic Hormones In Vivo

   • Justin Silver, Ayal Epstein, Gideon Almogi, Tally Naveh-Many

   Pages 57-70

6. Effects of Estrogen on Growth Factors in Bone

   • Lynda F. Bonewald

   Pages 71-94

7. Estrogens, Cytokines, and Bone Metabolism

   • Stavros C. Manolagas

   Pages 95-118

8. Sex Steroids and Prostaglandins in Bone Metabolism

   • Webster S. S. Jee, Yanfei F. Ma, Mei Li, Xiaoquang G. Liang, Baiyun Y. Lin, Xiaojian J. Li et al.

   Pages 119-150

9. Animal Models for Osteoporosis

   • Hartmut H. Malluche, Janet B. Rodgers

   Pages 151-166

10. The Rat as an Animal Model of Postmenopausal Bone Loss

    • Dike N. Kalu

    Pages 167-181

11. Histomorphometric Studies of Bone Changes in Ovariectomized Rats and Their Prevention by Estrogen Replacement

    • Thomas J. Wronski, Chiung-Fen Yen

    Pages 183-190

12. Biochemical Assessment of Bone Metabolism in Rodents

    • Roman C. Mühlbauer

    Pages 191-202

13. Back Matter

    Pages 203-205

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Bone is a sex hormone-dependent organ, which has important implications for current therapeutic strategies in the prevention and possible treatment of bone loss in the elderly. This book contains the proceedings of the Schering Workshop on "Sex Steroids and Bone." The various chapters by leading experts give and overall view of current knowledge on the control of bone hemostasis by sex steroids and new ideas on how this controlcould be exerted. It was also of particular concern to integrate a general survey of in vivo experimentation and histomorphometric evaluation of bone tissue. The organizers of the workshop and editors of this volume hope that it will contribute to a better understanding of the role of sex steroids in bone and thus pave the way for a better experimental approach instudying drug effects on bone with the ultimate goal of improving therapy in bone diseases.

• Knochen
• Osteoporose
• Postmenopausale
• Sexualsteroide
• Tiermodelle für Osteoporose
• animal models for osteoporosis
• bone
• metabolism
• osteoporosis
• postmenopausal
• prevention
• sex steroids
• steroids
• tissue

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