Vogel and Motulsky's Human Genetics

1. Front Matter

   Pages I-XXXIV

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2. Introduction

   • Friedrich Vogel, Arno G. Motulsky

   Pages 1-8

3. History of Human Genetics

   • Friedrich Vogel, Arno G. Motulsky

   Pages 9-19

4. Human Chromosomes

   • Friedrich Vogel, Arno G. Motulsky

   Pages 20-110

5. Formal Genetics of Man

   • Friedrich Vogel, Arno G. Motulsky

   Pages 111-227

6. Gene Action

   • Friedrich Vogel, Arno G. Motulsky

   Pages 228-333

7. Mutation

   • Friedrich Vogel, Arno G. Motulsky

   Pages 334-432

8. Population Genetics

   • Friedrich Vogel, Arno G. Motulsky

   Pages 433-511

9. Human Evolution

   • Friedrich Vogel, Arno G. Motulsky

   Pages 512-542

10. Genetics and Human Behavior

    • Friedrich Vogel, Arno G. Motulsky

    Pages 543-613

11. Practical Applications of Human Genetics and the Biological Future of Mankind

    • Friedrich Vogel, Arno G. Motulsky

    Pages 614-641

12. Back Matter

    Pages 642-810

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The first edition of this book, published in 1979, was found useful by many stu­ dents and was well received by the scientific community. Since the book was first written, human genetics has undergone dramatic developments, mainly due to the introduction of new concepts and techniques from molecular biology. Con­ comitantly, "basic" scientists have become increasingly interested in problems of human genetics. More than 700 human genes have been mapped, genes of previ­ ously unsuspected complexity -such as the gene for factor VIII - have become known, and the structure of noncoding DNA sequences is being analyzed with the aim of understanding gene regulation. DNA diagnosis is being rapidly intro­ duced into medical genetics. All this, as well as the extensive progress in most other fields of human and medical genetics, had to be considered in the prepara­ tion of this second edition. The book has been extensively revised and rewritten. A substantial new section dealing with gene and chromosomal structure at the molecular level has been added. The newer knowledge of molecular genetics has been incorporated, and the conceptual and practical contribution of DNA methods (for example in the hemoglobinopathies and in some other diseases) is discussed. Many new figures and tables have been added, and some illustrative material has been replaced. We have read carefully the many friendly and sometimes flattering reviews of the first edition.

• Chromosom
• DNA
• Genetic Analysis
• gene therapy
• genes
• genetics
• heredity
• human development
• human evolution
• inborn diseases
• prenatal diagnosis

"I know of no other book which has the sheer authority of Vogeland Motulsky." - Genetica Research Cambridge "Encyclopedia Genetica Humana could have been the title of this book for it contains all that a student of genetics might want to know about this discipline." - Immunogenetics

• Institut für Anthropologie und Humangenetik, Heidelberg, Germany

  Friedrich Vogel

• Division of Medical Genetics, University of Washington, Seattle, USA

  Arno G. Motulsky

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