Between Moral Hazard and Legal Uncertainty

1. Front Matter

   Pages I-IX

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2. Between Moral Hazard and Legal Uncertainty

   • Matthias Braun, Hannah Schickl, Peter Dabrock

   Pages 1-14

3. Mapping the Current Legal Framing

   1. Front Matter

      Pages 15-15

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   2. Genome Editing and the Law

      • Stephan Rixen

      Pages 17-30

   3. Integrating Ethical Standards into the Human Rights Framework

      • Fruzsina Molnár-Gábor

      Pages 31-50

4. Theoretical Challenges

   1. Front Matter

      Pages 51-51

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   2. Prospects of Human Germline Modification by CRISPR-Cas9 – an Ethicist’s View

      • Dieter Birnbacher

      Pages 53-66

   3. Genome Editing, Non-Identity and the Notion of Harm

      • Alina Omerbasic

      Pages 67-81

   4. Genome Editing and the Transgression of the Species Boundary

      • Markus Rothhaar

      Pages 83-97

   5. Germline Modifications as a Severe Intervention into Human Nature

      • Nadia Primc

      Pages 99-110

   6. Is Genome Editing Unnatural?

      • Eva Odzuck

      Pages 111-128

   7. Transition and Care

      • Mathias Wirth

      Pages 129-148

   8. Human Germline Genome Editing in the Clinical Context

      • Giovanni Rubeis

      Pages 149-160

5. Towards a Governance Frame in Dealing with Genome Editing

   1. Front Matter

      Pages 161-161

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   2. Who? What? How? Why? If You Don’t Ask You’ll Never Know …

      • Peter Dabrock

      Pages 163-185

   3. Debating Genome Editing Technologies

      • Lukas Kaelin

      Pages 187-201

   4. A Path Through the (Moral) Morass

      • Giulia Cavaliere

      Pages 203-225

Genome Editing Techniques are seen to be at the frontier of current research in the field of emerging biotechnologies. The latest revolutionary development, the so-called CRISPR technology, represents a paradigmatic example of the ambiguity of such techniques and has resulted in an international interdisciplinary debate on whether or not it is necessary to ban the application of this technique by means of a moratorium on its use for human germline modifications, particularly in human embryos in the reproduction process. However, given that other germline engineering techniques like mitochondrial (mt) DNA transfer techniques are already permitted and applied, the question arises what lies at the root of the apparent social unease about the modification of the human germline by Genome Editing Techniques like CRISPR. Against this background, the book seeks to make a substantial contribution to the current debate about a responsible and participatory framework for research on emerging biotechnologies by analysing underlying perceptions, attitudes, arguments and the reasoning on Genome Editing Techniques.

• CRISPR
• Genome Editing
• Ethics
• RRI
• Practical Ethics
• research ethics

• Chair of Systematic Theology II (Ethics), Friedrich-Alexander-Universität , Erlangen, Germany

  Matthias Braun

• Interdisciplinary Research Group “Gene Technology Report”, Berlin-Brandenburg Academy of Sciences and Humanities, Berlin, Germany

  Hannah Schickl

• Chair of Systematic Theology II (Ethics), Friedrich-Alexander-Universität, Erlangen, Germany

  Peter Dabrock

Matthias Braun is assistant Professor at the Chair of Systematic Theology II (Ethics), Friedrich-Alexander University Erlangen-Nuremberg.


Hannah Schickl is research assistant in the Interdisciplinary Research Group “Gene Technology Report”, Berlin-Brandenburg Academy of Sciences and Humanities.


Peter Dabrock is Professor of Systematic Theology/Ethics at the Friedrich-Alexander University Erlangen-Nuremberg and Chair of the German Ethics Council.

Policies and ethics