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Table of contents (5 chapters)
Keywords
About this book
Matthias Würl presents two essential steps to implement offline PET monitoring of proton dose delivery at a clinical facility, namely the setting up of an accurate Monte Carlo model of the clinical beamline and the experimental validation of positron emitter production cross-sections. In the first part, the field size dependence of the dose output is described for scanned proton beams. Both the Monte Carlo and an analytical computational beam model were able to accurately predict target dose, while the latter tends to overestimate dose in normal tissue. In the second part, the author presents PET measurements of different phantom materials, which were activated by the proton beam. The results indicate that for an irradiation with a high number of protons for the sake of good statistics, dead time losses of the PET scanner may become important and lead to an underestimation of positron-emitter production yields.
Authors and Affiliations
About the author
Matthias Würl wrote his Master’s Thesis at the chair of Medical Physics at the Ludwig-Maximilians University Munich. He is now a PhD student at the same department, working on transmission imaging with laser-accelerated ions.
Bibliographic Information
Book Title: Towards Offline PET Monitoring at a Cyclotron-Based Proton Therapy Facility
Book Subtitle: Experiments and Monte Carlo Simulations
Authors: Matthias Würl
Series Title: BestMasters
DOI: https://doi.org/10.1007/978-3-658-13168-5
Publisher: Springer Spektrum Wiesbaden
eBook Packages: Physics and Astronomy, Physics and Astronomy (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Fachmedien Wiesbaden GmbH, part of Springer Nature 2016
Softcover ISBN: 978-3-658-13167-8Published: 03 June 2016
eBook ISBN: 978-3-658-13168-5Published: 30 May 2016
Series ISSN: 2625-3577
Series E-ISSN: 2625-3615
Edition Number: 1
Number of Pages: XV, 86
Number of Illustrations: 20 b/w illustrations, 10 illustrations in colour
Topics: Particle and Nuclear Physics, Theoretical, Mathematical and Computational Physics, Biological and Medical Physics, Biophysics