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Axoplasmic Transport in Physiology and Pathology

  • Conference proceedings
  • © 1982

Overview

Editors:
  1. Dieter G. Weiss

    1. Zoologisches Institut, Universität München, München 2, Germany

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  2. Alfredo Gorio

    1. Department of Cytopharmacology, Fidia Research Laboratories, Abano Terme, Padova, Italy

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Proceedings in Life Sciences (LIFE SCIENCES)

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Table of contents (24 papers)

  1. Front Matter

    Pages I-XI
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  2. General Properties of Axoplasmic Transport

    1. General Properties of Axoplasmic Transport

      • Dieter G. Weiss
      Pages 1-14

  3. The Physiological Role of Axoplasmic Transport

    1. Front Matter

      Pages 15-15
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    2. Axoplasmic Transport and Synaptic Transmission

      • Annica Dahlström
      Pages 16-20

    3. Effect of Physiological Activity in Goldfish Optic Axons on Axonal Transport of Protein and Nucleosides

      • Bernice Grafstein, D. Louise Edwards
      Pages 21-26

    4. Fate of Axonally Transported Proteins in the Nerve Terminal

      • Mats Sandberg, Anders Hamberger, Ingemar Jacobsson, Jan-Olof Karlsson
      Pages 27-31

    5. Transneuronal Transport: A Way for the Neuron to Communicate with Its Environment

      • Peter Schubert, Georg W. Kreutzberg
      Pages 32-43

    6. Axonal Transport, Neurosecretory Vesicles, and the Endocrine Neuron

      • Harold Gainer, James T. Russell, Michael J. Brownstein
      Pages 44-50

  4. The Role of Axoplasmic Transport in Growth and Regeneration

    1. Front Matter

      Pages 51-51
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    2. Axonal Transport in the Sprouting Neuron: Transfer of Newly Synthesized Membrane Components to the Cell Surface

      • Karl H. Pfenninger
      Pages 52-61

    3. The Role of Axonal Transport in the Growth of the Olfactory Nerve Axons

      • P. Cancalon, G. J. Cole, J. S. Elam
      Pages 62-69

    4. Changes in Fast-Transported Protein in Regenerating Axons: Essential or Incidental?

      • Mark A. Bisby
      Pages 70-76

    5. Recovery of Axonal Transport of Acetylcholinesterase in Regenerating Sciatic Nerve Precedes Muscle Reinnervation

      • Luigi Di Giamberardino, Jean-Yves Couraud, Raymonde Hässig, Alfredo Gorio
      Pages 77-80

    6. The Role of Axoplasmic Transport in the Restoration of Synaptic Transmission and in the Process of Sprouting During Nerve Regeneration

      • Alfredo Gorio
      Pages 81-89

  5. Experimental Neuropathies and Axoplasmic Transport

    1. Front Matter

      Pages 91-91
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    2. Disruption of Axoplasmic Transport by Neurotoxic Agents. The 2,5-Hexanedione Model

      • Peter S. Spencer, John W. Griffin
      Pages 92-103

    3. Axoplasmic Transport in the Experimental Neuropathy Induced by Acrylamide

      • Bernard Droz, Monique Chretien, Françoise Souyri, Gilles Patey
      Pages 104-108

    4. Axonal Transport in β,β’-Iminodipropionitrile Neuropathy

      • John W. Griffin, Paul N. Hoffman, Donald L. Price
      Pages 109-118

    5. Disulfiram-Induced Impairment of Horseradish Peroxidase Retrograde Transport in Rat Sciatic Nerve

      • Archinto P. Anzil, Gerhard Isenberg, Georg W. Kreutzberg
      Pages 119-122

  6. Neuronal Pathology and Axoplasmic Transport

    1. Front Matter

      Pages 123-123
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Keywords

About this book

Cajal and contemporary scientists have laid the basis of the modem concepts of the organization of the nervous system: the cir­ cuits of the brain are made up of individual neurons which transfer information via specialized structures called synapses. Soma and den­ drites usually receive the inputs, then the signal is carried all along the axon to the target areas. To fulfIll this task several types of neurons have developed their unique geometry characterized by a large recep­ tive area (soma and dendrites) and an often very extensive distal branching with the axon terminals. The volume of cytoplasm which constitutes the neuronal periphery is often far larger than the cell body, where the synthetic machinery is located. It is one of the roles ofaxoplasmic transport to supply the periphery with proper material and to sustain the specialized structures necessary for the physiological activity of the neuron. Furthermore, it has become more and more clear that target areas also exert effects on the innervating neurons, and these effects are not only mediated via recurrent fibers. Synapses have been shown to be able to pick up material from the synaptic left which is then intra­ axon ally transported back to the cell body. This retrograde axoplasmic transport has therefore been recognized as another basic mechanism to convey signals from the periphery to the centre.

Editors and Affiliations

  • Zoologisches Institut, Universität München, München 2, Germany

    Dieter G. Weiss

  • Department of Cytopharmacology, Fidia Research Laboratories, Abano Terme, Padova, Italy

    Alfredo Gorio

Bibliographic Information

  • Book Title: Axoplasmic Transport in Physiology and Pathology

  • Editors: Dieter G. Weiss, Alfredo Gorio

  • Series Title: Proceedings in Life Sciences

  • DOI: https://doi.org/10.1007/978-3-642-85714-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1982

  • Softcover ISBN: 978-3-642-85716-4Published: 10 April 2012

  • eBook ISBN: 978-3-642-85714-0Published: 06 December 2012

  • Series ISSN: 0172-6625

  • Edition Number: 1

  • Number of Pages: XI, 192

  • Number of Illustrations: 43 b/w illustrations, 2 illustrations in colour

  • Topics: Neurosciences

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