Overview
- Editors:
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P. R. Lichtlen
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Abtl. Innere Medizin/Kardiologie, Medizinische Hochschule Hannover, Hannover 61, Germany
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A. Reale
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Cardiologia Policlinico, Roma, Italy
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Table of contents (24 papers)
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Adalat: Historical Aspects from the Cardiologist’s View
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The History of Nifedipine in Japan
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History of Adalat
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- P. G. Hugenholtz, C. van Halem, F. J. van Dalen, M. van den Brand
Pages 39-54
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Lectures
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Hypertension
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- I.-W. Franz, R. Ketelhut, U. Behr, U. Tönnesmann
Pages 83-95
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- I.-W. Franz, U. Tönnesmann, D. Erb, R. Ketelhut
Pages 96-102
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- J. B. Pevahouse, N. D. Markandu, F. P. Cappuccio, M. G. Buckley, G. A. Sagnella, G. A. MacGregor
Pages 103-112
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- M. Fujishima, K. Ueda, Y. Hasuo, Y. Kiyohara, I. Abe
Pages 117-126
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Coronary Heart Disease
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- W. G. Nayler, Xin Hua Gu, M. J. Daly, S. L. Brittnell
Pages 129-138
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- D. Tzivoni, J. Benhorin, A. Gavish, S. Stern
Pages 139-144
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About this book
As little as 30 years ago, cardiovascular research at Bayer was just a small sideline with in an environment dominated by chemotherapy research, and only 15 years ago, Bayer's pharmaceutical business was confined to European and Latin Ameri can countries, with sales in cardiovascular pharmaceuticals close to zero. It goes without saying that Adalat has changed the company as a whole in its research, development, and marketing, both in Germany and, most importantly, world wide. In research and development, Adalat has led the way in to new areas such as hypertension, acute neurology, dementia, atherosclerosis, and heart failure. In pharmacology, Adalat was present at the dawning of the second phar macological revolution, which started out from whole animal models and progres sed, via in vitro screening and pharmacological research on the DHP receptor, down to the molecular level with the cloning of calcium-channel proteins. Having followed the Adalat story closely in its early years as a bench scientist, let me take this opportunity to thank the inventors, the scientists, and the investigators who have helped to tap the broad potential of calcium-channel blockade with dihyd ropyridines in general and Adalat in particular. But, success should not obscure our vision. There is no reason for us to rest on our laurels: it will take true innovations in cardiovascular research to top the gold standard set by Adalat. Let us take up the challenge.
Editors and Affiliations
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Abtl. Innere Medizin/Kardiologie, Medizinische Hochschule Hannover, Hannover 61, Germany
P. R. Lichtlen
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Cardiologia Policlinico, Roma, Italy
A. Reale
