Cardiac Adaptation to Hemodynamic Overload, Training and Stress

1. Front Matter

   Pages I-X

   PDF

2. Editorial

   1. Front Matter

      Pages 1-1

      PDF

   2. Chronic reactions of myocardium at the myofibrillar level Reflections on “adaptation” and “disease” based on the biology of long-term cardiac overload

      • R. Jacob

      Pages 3-24

3. Fundamental biochemical processes — Control of myocardial cell growth and gene expression

   1. Front Matter

      Pages 25-25

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   2. Molecular dynamics of contraction—relaxation

      • J. Gergely

      Pages 27-32

   3. Effects of activity on some physiological properties of skeletal muscles

      • G. Vrbová

      Pages 33-38

   4. Relationship between the synthesis rates and mRNA levels of the α and β cardiac myosin heavy chains in normal and thyrotoxic rabbits

      • A. W. Everett, A. M. Sinha, M. Rabinowitz, Radovan Zak

      Pages 39-45

   5. Dissociation between factors resulting in hypertrophy and changes in myosin isoenzyme population of the pressure-loaded rat heart

      • H. Rupp, N. Popova, R. Jacob

      Pages 46-52

   6. Dissociation of hypertrophy and altered function in senescent rat myocardium

      • E. G. Lakatta

      Pages 53-58

   7. Differential effect of thyroid hormones on catecholamine enzymes and myosin isoenzymes in ventricles and atria of the rat heart

      • A. R. Bukhari, H. Rupp

      Pages 59-64

   8. The adrenals in experimental cardiac hypertrophy

      • František Kölbel, V. Schreiber, J. Štěpán, T. Přibyl, I. Gregorová

      Pages 65-68

   9. Myocardial nucleus in growing and hypertrophied heart

      • F. Cluzeaud, J. Perennec, E. de Amaral, M. Wiliemin, P. Y. Hatt

      Pages 69-69

   10. A pathomorphological study on the diabetogenic drug-induced heart disease in the rat

       • Shunzo Onishi, H. Nunotani, Y. Tochino

       Pages 70-77

   11. The role of cyclic nucleotides in the pathogenesis of myocardial hypertrophy

       • N. Popova, B. Bozhkov, R. Kolarova, I. Petkova

       Pages 78-82

   12. The role of cytoplasmic factors in RNA synthesis activation during hyperfunction of heart and liver

       • F. Z. Meerson, M. P. Yavich

       Pages 83-93

   13. New trends in biology of cardiac overload: plasma membranes, enzymes, cytoskeleton proteins and in vitro traduction of RNA

       • P. Mansier, K. Schwartz, L. Lelievre, J. M. Moalic, D. Charlemagne, J. Lu Samuel et al.

       Pages 94-98

4. Structural changes of contractile proteins

   1. Front Matter

      Pages 99-99

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   2. Adaptive changes in cardiac isomyosins as visualized by immunofluorescence

      • S. Schiaffino, L. Gorza, S. Sartore, C. Valfré, P. Pauletto

      Pages 101-103

   3. Myosin isoenzymic distribution in hyperthrophied rat and human hearts

      • J. J. Mercadier, A. M. Lompré, P. Bouveret, J. L. Samuel, L. Rappaport, B. Swynghedauw et al.

      Pages 104-112

   4. Thyroxine-induced molecular alteration of heavy and 27,000-dalton light chains of rabbit ventricular myosin. Reconstitution of heavy and light chain molecules of subfragment-1 isozymes of cardiac myosin

      • S. Ueda, Y. Yazaki

      Pages 113-122

Cardiac hypertrophy and accompanying phenomena have received increasing attention in recent years - particularly in the basic sciences. The present volume contains the proceedings of the Erwin RIESCH SYMPOSIUM on "CARDIAC ADAPTATION TO HEMODYNAMIC OVERLOAD, TRAINING AND STRESS" held in Tiibingen on Sep­ tember 19-22, 1982. In addition to the topics of the previous symposia (1976 and 1979) concerned with problems of cardiac hypertrophy, the scope of this sequel meeting has been expanded to include related fields. The intention was to consider numerous related features and problems of chronic reactions of the heart (and vascular system) to abnormal hemodynamic loading, as well as alterations due to maturation, aging, training, neuroendocrine status and stress. Special attention has been paid to cardiac reactions at the level of contractile proteins. The results are considered primarily in light of long-term adaptation of the heart. Of course, research at the forefront of current knowledge need not always lead to congruent conclusions. Neither can the individual contributions always agree with the viewpoint of the editors. However, the broad array of individual approaches employed by biochemists, biolo­ gists, pathologists, physiologists, pharmacologists and clinical cardio­ logists will certainly help to provide a more balanced interpretation of the results in individual fields, stimulate reexamination of established con­ cepts and provide direction for future research.

• adaptation
• aging
• artery
• attention
• blood pressure
• cardiovascular
• circulation
• heart
• heart disease
• hypertension
• lead
• pharmacology
• protein
• proteins
• research

• Tübingen, Germany

  G. Kissling

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