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Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes

  • Book
  • © 1994

Overview

Editors:
  1. Yechiel Becker

    1. Department of Molecular Virology, Institute of Microbiology, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

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  2. Gholamreza Darai

    1. Institut für Medizinische Virologie, Universität Heidelberg, Heidelberg, Germany

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Frontiers of Virology (FRVIROLOGY, volume 3)

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Table of contents (22 chapters)

  1. Front Matter

    Pages I-XVI
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  2. Herpes Simplex Virus

    1. Front Matter

      Pages 1-1
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    2. Genes Involved in Entry

      1. Entry of Herpes Simplex Virus Type 1 into Cells — Early Steps in Virus Pathogenicity
        • Yechiel Becker, Eynat Tabor, Yael Asher, Mirta Grifman, Yosef Kleinman, Avner Yayon
        Pages 3-20
      2. Neomycin and Herpes Simplex Virus Receptor Binding: The Role of Glycoprotein C
        • Anne M. Øyan, Lars Haarr, Joseph C. Glorioso, Karen E. Dolter, Howard S. Marsden, Clyde S. Crumpacker et al.
        Pages 21-32
      3. Pathogenicity of Glycoprotein C-Negative Herpes Simplex Virus Type 1 in Herpetic Keratitis
        • Yasushi Toh, Yasufumi Hidaka, Yuji Kumano, Hiroko Minagawa, Ryoichi Mori
        Pages 33-42
      4. Structure and Function of Glycoprotein D of Herpes Simplex Virus
        • R. J. Eisenberg, D. Lone, D. L. Sodora, H.-Y. Chiang, W. C. Wilcox, W. R. Abrams et al.
        Pages 43-65

    4. Genes Related to Intraperitoneal Pathogenicity

      1. Effect of Herpes Simplex Virus Type 1 <i>UL41</i> Gene Product on <i>mdr-1</i> Gene-mRNA in Infected Adrenal Glands
        • Michal Moyal, Yechiel Becker
        Pages 170-176
      2. Pathogenicity and Latency of Herpes Simplex Virus in the Animal Model System Tree Shrew
        • Angela Rösen-Wolff, Roland Kehm, Eva Lorentzen, Wolfram Lamade, Gholamreza Darai
        Pages 177-202
      3. Computer Analysis of the Protein Coded by Herpes Simplex Virus Type 1 <i>UL56</i> Gene
        • Mirta Grifman, Yechiel Becker
        Pages 203-207

    5. Genes and Latency and Intracerebral Pathogenicity

      1. The Herpes Simplex Type 1 Virus Latency Gene
        • Edward K. Wagner
        Pages 210-221
      2. Neurovirulence of Herpes Simplex Virus Type 1 Accessory Gene Mutants
        • Myron Levine, David J. Fink, Ramesh Ramakrishnan, Prashant Desai, William F. Goins, Joseph C. Glorioso
        Pages 222-237
      3. Herpes Simplex Virus Latency and Immediate Early Gene Repression by the Cellular Octamer-Binding Protein Oct-2
        • David S. Latchman
        Pages 238-252
      4. The Cell Fusion Protein Gene (<i>UL53</i>) of Herpes Simplex Virus Type 1 — A Pathogenicity Gene
        • Michal Moyal, Yechiel Becker
        Pages 253-260

    6. Genes and Latency and Intracerebral Pathogenicity

      1. Role of Langerhans Cells and Other Dendritic Cells in the Pathogenesis of Herpes Simplex Virus Type 1 Infection
        • Eli Sprecher, Yechiel Becker
        Pages 262-280

  3. Epstein Barr Virus

    1. Front Matter

      Pages 281-281
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    2. Gene Expression in Burkitt’s Lymphoma Cells

      • Marc Jacquemin, Alison J. Sinclair, Paul J. Farrell
      Pages 283-297
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Keywords

About this book

Six members of the Herpesviridae family are human pathogens, including herpes and 2 (HSV-I and 2), Epstein-Barr virus (EBV), varicella zoster simplex virus I virus (VZV), human cytomegalovirus (HCMV), and human herpesvirus 6 (HHV 6). Each of these viruses is capable of causing distinct diseases of varying severity in children, young adults, and the aged. The diseases range from infection of epithelial tissue to the infection of internal organs and white blood cells. A common feature of the six pathogenic human herpesviruses is their ability to latently infect different cell types in which the viral DNA is not integrated and is unable to express its pathogenicity. Reactivation of the herpesviruses is a result of cellular processes which reactivate viral genes, leading to virus progeny and to signs of infection. Due to their ability to become latent after initial infection, once the pathogenic herpesviruses infect children they are maintained throughout life, having the potential of cause various diseases upon reactivation.

Editors and Affiliations

  • Department of Molecular Virology, Institute of Microbiology, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

    Yechiel Becker

  • Institut für Medizinische Virologie, Universität Heidelberg, Heidelberg, Germany

    Gholamreza Darai

Bibliographic Information

  • Book Title: Pathogenicity of Human Herpesviruses due to Specific Pathogenicity Genes

  • Editors: Yechiel Becker, Gholamreza Darai

  • Series Title: Frontiers of Virology

  • DOI: https://doi.org/10.1007/978-3-642-85004-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1994

  • Softcover ISBN: 978-3-642-85006-6Published: 15 December 2011

  • eBook ISBN: 978-3-642-85004-2Published: 06 December 2012

  • Series ISSN: 1431-357X

  • Edition Number: 1

  • Number of Pages: XVI, 387

  • Topics: Virology, Microbiology, Cell Biology, Biochemistry, general, Internal Medicine

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