Practical Approaches to Cancer Invasion and Metastases

1. Front Matter

   Pages I-XI

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2. Introduction

   1. Introduction

      • A. Robert Kagan, Richard J. Steckel

      Pages 1-3

3. Prolong Life

   1. Front Matter

      Pages 5-5

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   2. Advanced Rhabdomyosarcoma of the Sinus

      • Edward C. Halperin

      Pages 7-11

   3. Advanced Cancer of the Hypopharynx

      • Lester J. Peters, Helmuth Goepfert

      Pages 12-15

   4. Paraplegia

      • J. Frank Wilson, Kevin Murray

      Pages 16-17

   5. Melanomatosis with Abnormal Cerebral Computed Tomography Scan

      • Monica Ryoo

      Pages 18-19

   6. Multiple Cerebral Metastasis from Cancer of the Lung

      • Milton Raben

      Pages 20-21

   7. Superior Vena Cava Syndrome

      • James E. Marks

      Pages 22-23

   8. Widely Disseminated Breast Cancer and Hypercalcemia

      • Jonathan Tsao

      Pages 24-25

   9. Palliative Treatment of Cancer of the Pancreas

      • Carl M. Mansfield

      Pages 26-31

   10. Recurrent Cervical Cancer with Positive Para-aortic Nodes

       • Henry M. Keys

       Pages 32-33

4. Preventive or Anticipatory Irradiation

   1. Front Matter

      Pages 35-35

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   2. Extragonadal Choriocarcinoma

      • Alfred L. Goldson

      Pages 37-39

   3. Mammary Adenocarcinomatosis Complicated by Vertebral Destruction

      • Stanton A. Marks

      Pages 40-45

   4. Cord Compression

      • Anas M. El-Mahdi

      Pages 46-48

   5. Advanced Locoregional Breast Cancer

      • John Bedwinek

      Pages 49-51

   6. Abnormal Cerebral Computed Tomography Scan Status Post Lung Cancer

      • H. D. Kerman

      Pages 52-54

   7. Positive Prostate Biopsy Post Irradiation

      • T. J. Brickner Jr

      Pages 55-57

   8. Metastatic Lymphoma and Spinal Cord Compression

      • Thomas A. Buchholz, Thomas W. Griffin

      Pages 58-62

In the United States in 1993 the American Cancer Society estimated that there were about 1,300,000 new cases of invasive cancer diagnosed. At the time of presentation about 70% of those patients represented limited local regional disease without evidences of distant dissemination. About 30% of the patients had demonstrated metastatic disease at the time of initial diagnosis or about 390,000 patients. Of those patients with local regional disease about 56% would be cured by the best treatment programs including surgery, radiation therapy with or without chemotherapy when given for cure. Therefore, of the 1,300,000 new cases of invasive cancer, about 509,000 would be cured by the best treatments available. However, about 790,000 patients will have metastatic disease as a part of initial presentation or following the completion of definitive treatment. The majority of the patients with metastatic disease will have metastases to bone as the dominant site of metastatic disease primarily from cancers of the breast and lung but other metastatic sites will be common including lung, liver, mediastinal and retro-peritoneallymph node groups as well as brain and spinal cord. It has been suggested by SMITHERS, CARLING and WINDEYER that the management of the patient with metastatic disease or recurrent disease can be a more difficult problem in management than a patient who is treated for cure.

• biopsy
• brain
• breast cancer
• cancer
• computed tomography (CT)
• imaging
• lymphoma
• magnetic resonance imaging (MRI)
• metastasis
• metastatic disease
• oncology
• radiation
• radiology
• radiotherapy
• tomography
• Radiaton Oncology

• Department of Radiation Oncology, Southern California Permanente Medical Group, Los Angeles, USA

  A. Robert Kagan

• Center for Health Sciences, Johnsson Cancer Center, University of California, Los Angeles, Los Angeles, USA

  Richard J. Steckel

Policies and ethics