Skip to main content
SpringerLink
Log in

Cancer Therapy

Differentiation, Immunomodulation and Angiogenesis

  • Conference proceedings
  • © 1993

Overview

Editors:
  1. Natale D’Alessandro

    1. Institute of Pharmacology, Messina, Italy

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Enrico Mihich

    1. Grace Cancer Drug Center, Department of Experimental Therapeutics, Roswell Park Center Institute, Buffalo, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Luciano Rausa

    1. Policlinic of the University “P. Giaccone”, Palermo, Italy

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  4. Haim Tapiero

    1. Laboratoire de Pharmacologie Cellulaire & Moleculaire, ICIG, Hopital Paul-Brousse, Villejuif, France

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  5. Thomas R. Tritton

    1. School of Medicine, University of Vermont, Burlington, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Nato ASI Subseries H: (ASIH, volume 75)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (24 papers)

  1. Front Matter

    Pages I-XI
    Download chapter PDF

  2. Colon Cancer Cell Differentiation as Related to Methotrexate and 5-Fluorouracil Resistance

    • A. Zweibaum, T. Lesuffleur, A. Barbat, E. Dussaulx, I. Chantret, L. Mahraoui et al.
    Pages 1-15

  3. The Control of Cell Multiplication and Differentiation in Human Myelomonocytic Cells

    • E. Huberman, D. A. Tonetti, M. Horio, S. Murao, F. R. Collart
    Pages 17-32

  4. Signal Transduction Through the Epstein-Barr Virus Receptor in Human B Lymphocytes

    • R. Frade
    Pages 33-38

  5. Signal Transduction Mechanisms as a Target for Cancer Chemotherapy

    • Thomas R. Tritton
    Pages 39-49

  6. Therapeutic Approaches for Colon Cancer Based on Transcriptional Regulation of Specific Growth Factors

    • M. G. Brattain, K. M. Mulder
    Pages 51-69

  7. Interferon Regulation of Differentiation and Mechanisms

    • G. B. Rossi, G. Romeo, A. Battistini, E. Affabris, E. M. Coccia, G. Fiorucci
    Pages 71-89

  8. Induction of Tumor Cell Differentiation as a Mechanism of Action of DNA-Specific Antitumor Agents

    • Alexander Bloch
    Pages 91-98

  9. ATRA Therapy in Acute Promyelocytic Leukemia a Model for Differentiation Therapy

    • Laurent Degos
    Pages 99-108

  10. Hemin is Transported in Human Leukemia K562 Cells and Interacts with DNA Sequences

    • Asterios S. Tsiftsoglou, Athina I. Tsamadou, Stephen H. Robinson, Willie Wong
    Pages 109-120

  11. Immunomodulation by Anticancer Drugs in Therapeutics

    • Enrico Mihich, M. Jane Ehrke
    Pages 121-133

  12. Differential Effects of Low Doses Of Structurally Different Anthracyclines on Immunoglobulin Production by Mouse Hybridoma B Cells

    • J.-L. Teillaud, H. Tapiero
    Pages 135-145

  13. Chemical Xenogenization of Experimental Tumors by Antineoplastic Drugs

    • P. Puccetti, U. Grohmann, R. Bianchi, L. Binaglia, M. L. Belladonna, M. Allegrucci et al.
    Pages 147-161

  14. Reversal of Drug Resistance: Synergistic Anti-Tumor Cytotoxic Activity by Combination Treatment with Drug and TNF or Toxins

    • Benjamin Bonavida, Jeffrey T. Safrit, Hideki Morimoto
    Pages 163-177

  15. Immunomodulation in Cancer Patients Treated with Interleukin-2. Induction of Non-Specific and Specific Immune Responses

    • Carlo Gambacorti-Passerini, Giorgio Parmiani, Pier Adelchi Ruffini
    Pages 179-187

  16. Potential Role of Tumor Cell Antigen Modulation in Cancer Immunotherapy

    • F. Guadagni
    Pages 189-200

  17. Effects of Tumor Necrosis Factor-Alpha on Growth and Doxorubicin Sensitivity of Multidrug Resistant Tumor Cell Lines

    • M. Crescimanno, N. Borsellino, V. Leonardi, L. Rausa, N. D’Alessandro
    Pages 201-208

  18. Activation of Macrophages by Treatment of Rat Peritoneal Cells with Photofrin II and He-Ne Laser

    • V. F. Dima, M. Ionescu, V. Vasiliu, S. V. Dima
    Pages 209-215

  19. Synergic Interaction between Simvastatin and Antineoplastic Drugs on Glioma Cell Growth

    • M. R. Soma, R. Baetta, C. Ferrari, M. R. de Renzis, R. Paoletti, R. Fumagalli
    Pages 217-223

  20. CNS and Cardiovascular Effects of TNF-α

    • F. Squadrito, A. P. Caputi
    Pages 225-230
Back to top

Keywords

About this book

Provided here is a comprehensive examination of the basic and clinical condition of three innovative and promising approaches to cancer therapy, which may support or even substitute chemotherapy: differentiation, immunomodulation, and inhibition of angiogenesis. Differentiation shouldnormalize neoplastic cells and make them compatible with the host. Its feasibility with retinoids, interferons, chemotherapeutic and other agents is discussed. Modulation by biological agents, cytotoxic effector cells and drugs is considered in attempts to boost endogenous antitumour defenses and/or to render neoplastic cells more susceptible to the immune attack of the host. Finally, the important aspect of interfering with tumour blood vessel development and function is taken into account. Consideringthe importance that chemotherapy has in cancer treatment and in view of a more and more integrated strategy, the relationship between the aforementioned approaches and chemotherapeutic agents and chemoresistance is treated in detail.

Editors and Affiliations

  • Institute of Pharmacology, Messina, Italy

    Natale D’Alessandro

  • Grace Cancer Drug Center, Department of Experimental Therapeutics, Roswell Park Center Institute, Buffalo, USA

    Enrico Mihich

  • Policlinic of the University “P. Giaccone”, Palermo, Italy

    Luciano Rausa

  • Laboratoire de Pharmacologie Cellulaire & Moleculaire, ICIG, Hopital Paul-Brousse, Villejuif, France

    Haim Tapiero

  • School of Medicine, University of Vermont, Burlington, USA

    Thomas R. Tritton

Bibliographic Information

  • Book Title: Cancer Therapy

  • Book Subtitle: Differentiation, Immunomodulation and Angiogenesis

  • Editors: Natale D’Alessandro, Enrico Mihich, Luciano Rausa, Haim Tapiero, Thomas R. Tritton

  • Series Title: Nato ASI Subseries H:

  • DOI: https://doi.org/10.1007/978-3-642-84613-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1993

  • Softcover ISBN: 978-3-642-84615-1Published: 21 December 2011

  • eBook ISBN: 978-3-642-84613-7Published: 29 June 2013

  • Series ISSN: 1010-8793

  • Edition Number: 1

  • Number of Pages: XI, 288

  • Topics: Cancer Research, Oncology, Pharmacology/Toxicology, Cell Biology, Immunology

Publish with us

Policies and ethics

Back to top

Search

Navigation