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Infection Control in Intensive Care Units by Selective Decontamination

The Use of Oral Non-Absorbable and Parenteral Agents

  • Conference proceedings
  • © 1989

Overview

Editors:
  1. Hendrik K. F. Saene

    1. Medical Microbiology, Royal, Liverpool Hospital, Liverpool, UK

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  2. C. P. Stoutenbeek

    1. Intensieve Zorgen, Onze Lieve Vrouw Gasthuis, Amsterdam, The Netherlands

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  3. Peter Lawin

    1. Klinik für Anästhesiologie und operative Intensivmedizin, Westfälischen Wilhelms-Universität, Münster, Germany

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  4. I. McA. Ledingham

    1. The Faculty of Medicine, Health Sciences University, Al Ain, United Arab Emirates

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Part of the book series: Update in Intensive Care and Emergency Medicine (UICM, volume 7)

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Table of contents (57 papers)

  1. Front Matter

    Pages i-xv
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  2. Foreword

    1. Foreword

      • I. McA. Ledingham
      Pages 1-1

  3. Introduction

    1. Introduction

      • H. K. F. van Saene
      Pages 3-4

  4. Pathogenesis

    1. Front Matter

      Pages 5-5
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    2. Host Microorganism Relationship in Healthy People

      1. Classification of Microorganisms Based on Intrinsic Pathogenicity
        • J. A. Washington
        Pages 8-12
      2. Defence Against Colonization and Infection
        • C. A. Hart
        Pages 13-21
      3. Oropharyngeal/Gastrointestinal Carriage: Role in Endogenous Colonization and Infection
        • W. G. Johanson
        Pages 22-24
      4. Discussion
        • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 25-26

    3. Host Microorganism Relationship in the Critically Ill

      1. Impaired Colonization Defence of the Oropharynx
        • W. G. Johanson
        Pages 28-33
      2. Impairment of Defence of the Stomach and Intestine against Colonization in the Critically Ill Patient
        • L. D. Hudson
        Pages 34-41
      3. Pathogenesis of Colonization/Infection of Lower Airways (Endogenous <i>vs</i> Exogenous): Conventional Approaches to Infection Control
        • M. S. Niederman
        Pages 42-48
      4. Discussion
        • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 49-50

  5. The Conventional Approach to Infection Control

    1. Front Matter

      Pages 51-51
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    2. Clinical Studies

      1. Prospective Study of Colonization, Infection and Mortality Rates during Conventional Therapy: Glasgow Data [1]
        • G. Ramsay
        Pages 54-55
      2. Infection and Mortality Rates in Critically Ill Patients during Conventional Antibiotic Regimen
        • M. Sydow, H. Burchardi, T. A. Crozier, R. Rüchel, C. Busse, W. Seyde
        Pages 56-56
      3. A Prospective Study of Colonization and Infection in the Neonatal Surgical Unit at Alder Hey Children’s Hospital, Liverpool, UK
        • J. Walker
        Pages 57-57
      4. Surveillance of Nosocomial Infections in a Surgical ICU: A Prospective Study
        • U. Hartenauer
        Pages 58-58
      5. Prospective Study of Colonization, Infection and Mortality Rates during Conventional Therapy
        • H. Wiedeck
        Pages 59-59
      6. Infection Control in the ICU: Pattern of Colonization and Infection in Surgical Intensive Care Patients — a Prospective Study
        • A. J. H. Kerver, J. H. Rommes, E. A. E. Verhage
        Pages 60-60
      7. Discussion
        • Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 61-64
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Keywords

About this book

Selective decontamination is a technique which combines short-term and long-term antimicrobials to prevent or treat the acquisition and subsequent carriage of microorganisms causing late colonization and infections. The antimicrobials are selective in that they leave the indigenous, mostly anaerobic flora more or less intact, whilst the effective decontamination provides a genuine breakthrough in the endogenous route of pathogenesis. The improvements in decontamination techniques presented here offer significant reduction in infection related morbidity and mortality among trauma patients.

Editors and Affiliations

  • Medical Microbiology, Royal, Liverpool Hospital, Liverpool, UK

    Hendrik K. F. Saene

  • Intensieve Zorgen, Onze Lieve Vrouw Gasthuis, Amsterdam, The Netherlands

    C. P. Stoutenbeek

  • Klinik für Anästhesiologie und operative Intensivmedizin, Westfälischen Wilhelms-Universität, Münster, Germany

    Peter Lawin

  • The Faculty of Medicine, Health Sciences University, Al Ain, United Arab Emirates

    I. McA. Ledingham

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