Cholesterol Transport Systems and Their Relation to Atherosclerosis

1. Front Matter

   Pages I-XIII

   PDF

2. Regulation of Cholesterol Metabolism

   1. Front Matter

      Pages 1-1

      PDF

   2. Receptors in the Regulation of Cholesterol Metabolism

      • J. Shepherd, C. J. Packard

      Pages 3-10

   3. Apolipoprotein E Modulates the Metabolism of Apolipoprotein B Containing Lipoproteins by Multiple Mechanisms

      • R. E. Gregg, L. A. Zech, C. Gabelli, H. B. Brewer Jr.

      Pages 11-21

   4. Regulation of Macrophage Cholesterol Homeostasis

      • G. Schmitz, B. Brennhausen, H. Robenek

      Pages 22-31

3. Hypercholesterolemia, LDL- and Scavenger Pathway

   1. Front Matter

      Pages 33-33

      PDF

   2. Familial Combined Hyperlipidemia Workshop

      • S. M. Grundy, A. Chait, J. D. Brunzell

      Pages 35-44

   3. Lipoproteins and Atherosclerosis: Lessons from an Animal Model for Familial Hypercholesterolemia

      • T. Kita, M. Yokode, K. Ishii, N. Kume, Y. Nagano, H. Otani et al.

      Pages 45-52

   4. Use of RFLPs of the LDL Receptor Gene in Diagnosis of Familial Hypercholesterolaemia

      • H. Schuster, G. Wolfram, Ch. Keller, N. Zöllner

      Pages 53-55

   5. Lipoprotein Lp(a): Structure and Metabolism

      • V. W. Armstrong, H. Kratzin, D. Seidel

      Pages 56-63

   6. Genetic Polymorphism of Lipoprotein (a)

      • H. J. Menzel, H. G. Kraft, C. Duba, G. Utermann

      Pages 64-69

   7. Binding Sites for Modified Low-Density Lipoprotein on Macrophagocytic Cells: Implications for Atherogenesis?

      • H. A. Dresel, E. Ottnad

      Pages 70-73

   8. Removal of Low-Density Lipoproteins by Alternative Pathways

      • T. J. C. van Berkel, J. K. Kruijt, H. J. M. Kempen

      Pages 74-82

4. Reverse Cholesterol Transport

   1. Front Matter

      Pages 83-83

      PDF

   2. Reverse Cholesterol Transport

      • A. van Tol

      Pages 85-88

   3. Antiatherogenic Effect of Apolipoprotein A-I Containing Lipoproteins

      • N. Ghalim, A. Barkia, P. Puchois, R. Barbaras, G. Ailhaud, J. C. Fruchart

      Pages 89-91

   4. An Apo A-I Protein A Hybrid Used for the Study of HDL Receptor Binding and Endocytosis

      • H. M. Bond, L. Monaco, R. Cortese, K. E. Howell

      Pages 92-99

   5. Lipid Transfer Protein: Hyperalphalipoproteinemia and Cholesteryl Ester Transfer/Exchange Acitivity

      • J. E. M. Groener

      Pages 100-105

   6. Role of Apolipoprotein A-IV in Reverse Cholesterol Transport

      • A. Steinmetz

      Pages 106-112

A number of clinical and epidemiological studies have shown that disorders of lipoprotein metabolism constitute one of the most important risk factors for the development of atherosclerosis and coronary heart disease. This volume examines the state of the art of lipoprotein subclass metabolism and its relation to these diseases. The authors also report on new developments concerning the role of lipoprotein recptors, macrophages and apolipoprotein E polymorphism in cholesterol homeostasis. The combination of general outline form and very specific aspects of cholesterol transport will interest those in other disciplines following developments in the field, as well as those directly involved in lipoprotein research.

• Lipoprotein
• atherosclerosis
• heart
• high-density lipoprotein (HDL)
• homeostasis
• metabolism
• protein
• metabolic disease

• Abteilung Endokrinologie und Stoffwechsel Zentrum Innere Medizin, Philipps-Universität, Marburg, Federal Republic of Germany

  Armin Steinmetz, Hans Kaffarnik, Jürgen Schneider

Policies and ethics