Overview
- Editors:
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Hans Scheurlen
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Institut für Medizinische Biometrie und Informatik, Universität Heidelberg, Heidelberg, Germany
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Richard Kay
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Department of Probability and Statistics, University of Sheffield, Sheffield, Great Britain
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Michael Baum
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King’s College, School of Medicine and Dentistry, CRC Clinical Trials Centre, Rayne Institute, London, Great Britain
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Table of contents (29 papers)
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Heterogeneous Treatment Effects
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- H. E. Rockette, R. J. Caplan
Pages 49-54
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On Combining Information: Historical Controls, Overviews, and Comprehensive Cohort Studies
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- H. E. Rockette, C. K. Redmond
Pages 99-104
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- J. Cuzick, H. J. Stewart, R. Peto, M. Baum, B. Fisher, H. Host et al.
Pages 108-129
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Subjective Opinions and Informed Consent
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- S. M. Gore, A. O. Langlands, D. J. Spiegelhalter, H. J. Stewart
Pages 149-170
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About this book
The controlled clinical trial has become an essential part of the clinician's decision-making process. Clinical trials, however, still raise methodological problems that are important and at the same time controversial: subgroup analysis and interactions, meta-analy sis of similar trials, consideration of subjective clinical opinions and those of the public at large, assessment of quality of life, pre vention trials, and so on. In February 1987 we took our third step along the road to evaluating these issues in dialogues between cli nicians, psychologists, legal experts, and statisticians. The talks presented at the meeting were revised by the authors afterwards and have been rearranged by the editors to form a strictly organ 1 2 ized book. The two preceding meetings in 1978 and 1981 focused strongly on adjuvant therapy in primary breast cancer, but this top ic served merely as a nucleus in the third meeting. This meeting, although called the Third Heidelberg Symposium was forced to leave Heidelberg and in fact was held in Freiburg. Without the interest and enthusiasm of Professor Martin Schu macher and his colleagues in Freiburg the meeting would never have taken place. The meeting was generously supported again by the Federal Ministry of Research and Technology (Bundesministe rium flir Forschung und Technologie, BMFT) within the framework of the West German BMFT Breast Cancer Study Group. We are grateful, in particular, to Mr. Hans W. Herzog for his personal in volvement. Juni 1988 H. Scheurlen, R. Kay, M.
Editors and Affiliations
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Institut für Medizinische Biometrie und Informatik, Universität Heidelberg, Heidelberg, Germany
Hans Scheurlen
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Department of Probability and Statistics, University of Sheffield, Sheffield, Great Britain
Richard Kay
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King’s College, School of Medicine and Dentistry, CRC Clinical Trials Centre, Rayne Institute, London, Great Britain
Michael Baum
