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HLA in Narcolepsy

  • Book
  • © 1988

Overview

Editors:
  1. Yutaka Honda

    1. Neuropsychiatric Research Institute, Seiwa Hospital, Shinjuku-ku, Tokyo, Japan

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  2. Takeo Juji

    1. Blood Transfusion Service, Tokyo University Hospital, Bunkyo-ku, Tokyo, Japan

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (17 chapters)

  1. Front Matter

    Pages I-XII
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  2. Introduction

    • Y. Honda
    Pages 1-9

  3. An Overview of the HLA System

    • T. Juji
    Pages 10-23

  4. Clinical Features of Narcolepsy: Japanese Experiences

    • Y. Honda
    Pages 24-57

  5. HLA in Narcolepsy in Japan

    • K. Matsuki, Y. Honda, M. Satake, T. Juji
    Pages 58-75

  6. HLA in Narcolepsy/Cataplexy in the United Kingdom

    • C. B. Lock, K. I. Welsh, J. D. Parkes, A. So, D. C. Briggs, R. W. Vaughan et al.
    Pages 76-88

  7. HLA in Narcolepsy in France

    • M. Billiard, J. Seignalet, H. Betuel, A. Marcadet, L. Gebuhrel, A. C. Freidel et al.
    Pages 89-96

  8. HLA in Narcolepsy in Canada

    • J. Montplaisir, G. Poirier
    Pages 97-107

  9. HLA-DR2 and the Narcolepsy Syndrome: The Stanford Experience

    • C. Guilleminault, J. Holloman, C. Grumet, T. Kilduff, H. O. McDevitt, W. C. Dement et al.
    Pages 108-113

  10. Narcolepsy and HLA in the Federal Republic of Germany: Population and Family Data

    • K. Meier-Ewert, G. Mueller-Eckhardt, D. J. Schendel
    Pages 114-120

  11. Positive HLA-Dw2 in Narcolepsy

    • T. Naohara, Y. Honda, T. Juji
    Pages 121-129

  12. HLA-Linked Complement Markers in Narcolepsy

    • K. Tokunaga, K. Matsuki, T. Juji, Y. Honda
    Pages 130-136

  13. DNA Typing in Narcolepsy

    • H. Inoko
    Pages 137-149

  14. Immunological Features of Narcolepsy in Japan

    • K. Matsuki, T. Juji, Y. Honda
    Pages 150-157

  15. Immune Factors in Narcolepsy in the United Kingdom

    • J. D. Parkes, K. Welsh, N. Langdon, C. Lock
    Pages 158-171

  16. Disorders of Excessive Daytime Sleepiness Without Cataplexy, and Their Relationship with HLA in Japan

    • S. Harada, K. Matsuki, Y. Honda, T. Someya
    Pages 172-185

  17. HLA in Disorders of Excessive Daytime Sleepiness Without Cataplexy in Canada

    • J. Montplaisir, G. Poirier
    Pages 186-190

  18. Genetic Markers Other than HLA in Narcolepsy

    • A. Asaka, K. Matsuki, M. Uchikawa, T. Juji, Y. Honda
    Pages 191-201

  19. Back Matter

    Pages 203-208
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Keywords

About this book

The Second International Symposium on Narcolepsy was held at Fairchild Auditorium, Stanford University, on 6-7 July 1985 under the presidency of Drs. William C. Dement and Christian Guillemi­ nault. It succeeded the First International Symposium on Narco­ lepsy held in La Grande Motte, France, organized by Pierre Pas­ souant in July 1975 in commemoration of the 100th anniversary of the publication of Jean B. E. Gelineau's paper which proposed the naming of narcolepsy. At the second narcolepsy symposium, many important research reports on both basic and clinical aspects of narcolepsy were given by investigators from many countries of the world. Audience inter­ est was particularly attracted by the section on the relationship be­ tween HLA and narcolepsy, in which recent evidence that almost all narcoleptic patients are HLA-DR2 positive was reported by in­ vestigators from Japan, England, France, Canada, and the United States. The close relationship between the HLA antigens, hitherto considered as immune-related genetic markers encoded by genes on human chromosome 6, and narcolepsy appeared to open a new approach not only for the research of narcolepsy but also for the mechanism of sleep in general. Publication of all these new findings on the association of HLA and narcolepsy was considered; an outline was worked out and all the groups agreed to prepare a contribution covering the various aspects of this topic.

Editors and Affiliations

  • Neuropsychiatric Research Institute, Seiwa Hospital, Shinjuku-ku, Tokyo, Japan

    Yutaka Honda

  • Blood Transfusion Service, Tokyo University Hospital, Bunkyo-ku, Tokyo, Japan

    Takeo Juji

Bibliographic Information

  • Book Title: HLA in Narcolepsy

  • Editors: Yutaka Honda, Takeo Juji

  • DOI: https://doi.org/10.1007/978-3-642-83387-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1988

  • Softcover ISBN: 978-3-642-83389-2Published: 14 December 2011

  • eBook ISBN: 978-3-642-83387-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 208

  • Topics: Neurology, Psychiatry, Human Genetics, Allergology, Immunology

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