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Adjuvant Therapy of Primary Breast Cancer

  • Conference proceedings
  • © 1989

Overview

Editors:
  1. Hans-Jörg Senn

    1. Medizinische Klinik C, Kantonsspital, St. Gallen, Switzerland

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  2. Aron Goldhirsch

    1. Servizio Oncologico Cantonale, Ospedale Civico, Lugano, Switzerland

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  3. Richard D. Gelber

    1. Division of Biostatistics and Epidemiology, Dana-Farber Cancer Institute, Boston, USA

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  4. Bruno Osterwalder

    1. Abteilung für Hämatologie und Onkologie Medizinische Klinik C, Kantonsspital, St. Gallen, Switzerland

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 115)

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Table of contents (40 papers)

  1. Front Matter

    Pages I-XVI
    Download chapter PDF

  3. Neoadjuvant (Pre- and Perioperative) Therapy

    1. Experimental Basis and Clinical Reality of Preoperative (Neoadjuvant) Chemotherapy in Breast Cancer

      • J. Ragaz, J. H. Goldie, R. Baird, P. Rebbeck, V. Basco, A. Coldman
      Pages 28-35

    2. Neoadjuvant Chemotherapy in the Conservative Management of Breast Cancer: A Study of 252 Patients

      • C. Jacquillat, M. Weil, G. Auclerc, M.-F. Auclerc, D. Khayat, F. Baillet
      Pages 36-42

    3. Randomized Perioperative Therapy in Operable Breast Cancer: The Ludwig Trial V

      • A. Goldhirsch, R. D. Gelber
      Pages 43-53

    4. Is There a Role for Perioperative Adjuvant Cytotoxic Therapy in the Treatment of Early Breast Cancer?

      • J. Houghton, M. Baum, R. Nissen-Meyer, D. Riley, R. A. Hern
      Pages 54-61

  4. Problems of Rational Follow-up and Salvage Therapy

    1. Radiation Therapy in Prevention and Salvage of Local Relapse: Its Prognostic Implication

      • R. Hünig, J. M. Kurtz
      Pages 62-68

    2. Salvage Treatments in Relapsing Resectable Breast Cancer

      • P. Valagussa, C. Brambilla, M. Zambetti, G. Bonadonna
      Pages 69-76

    3. Time Course and Prognosis of Mammary Failure Following Breast-Conserving Therapy

      • J. M. Kurtz, J.-M. Spitalier, R. Amalric, H. Brandone, Y. Ayme, C. Bressac et al.
      Pages 77-82

    4. Detection of Recurrence: A Critical Assessment of Existing Methods and Programs

      • W. F. Jungi, A. I. Streit, L. Schmid, H.-J. Senn
      Pages 83-91

    5. Factors Associated with Local Recurrence as a First Site of Failure Following the Conservative Treatment of Early Breast Cancer

      • J. Boyages, A. Recht, J. Connolly, S. Schnitt, M. A. Rose, B. Silver et al.
      Pages 92-102

    6. Critical Review of Problems of Rational Follow-up and Salvage Therapy

      • D. C. Tormey
      Pages 103-105
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Keywords

About this book

The ultimate "consumer" of the data presented at conferences on the primary treatment of operable breast cancer is the patient, and when, as in this disease, the benefits of therapy are relatively mod­ est, the availability and interpretation of the data from trials be­ comes an issue of primary importance. The effects of present treat­ ment are in fact such that more patients relapse despite therapy than are estimated to benefit from it. It is, therefore, extremely dif­ ficult for the physician to recommend unequivocally one particular adjuvant treatment modality for the vast population of women with breast cancer. The interpretation of results from clinical research-oriented pro­ grams is constantly applied, however, in the treatment of breast cancer patients outside of clinical trials. From presented or publish­ ed data, many physicians extrapolate indications for the use of a given treatment regimen for their patients, perceiving it as the "best available therapy. " It is essential that the "best available therapy" be selected individually for each patient. However, considering the modest effect of treatment upon outcome, it is imperative that those who provide the data - those who are involved in both pa­ tient care and clinical research - make it known that the best cur­ rent treatment for the population of breast cancer patients is avail­ able within the framework of clinical trials. In this way not only present-day patients but also future ones will derive the greatest benefit.

Editors and Affiliations

  • Medizinische Klinik C, Kantonsspital, St. Gallen, Switzerland

    Hans-Jörg Senn

  • Servizio Oncologico Cantonale, Ospedale Civico, Lugano, Switzerland

    Aron Goldhirsch

  • Division of Biostatistics and Epidemiology, Dana-Farber Cancer Institute, Boston, USA

    Richard D. Gelber

  • Abteilung für Hämatologie und Onkologie Medizinische Klinik C, Kantonsspital, St. Gallen, Switzerland

    Bruno Osterwalder

Bibliographic Information

  • Book Title: Adjuvant Therapy of Primary Breast Cancer

  • Editors: Hans-Jörg Senn, Aron Goldhirsch, Richard D. Gelber, Bruno Osterwalder

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-83337-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1989

  • Softcover ISBN: 978-3-642-83339-7Published: 14 December 2011

  • eBook ISBN: 978-3-642-83337-3Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XVI, 296

  • Topics: Oncology, Gynecology, Surgery, Radiotherapy

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