Endolymphatic Radiotherapy in Maglignant Lymphomas

1. Front Matter

   Pages i-xii

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2. Present Position of Radical and Palliative Treatment of Malignant Lymphomas

   • Gianni Bonadonna

   Pages 1-22

3. Lymphangiography and Endolymphatic Radiotherapy: General Principles

   • S. Chiappa, R. Musumeci, C. Uslenghi

   Pages 23-30

4. Technique of Lymphography and Endolymphatic Radiotherapy

   • Bruno Damascelli

   Pages 31-37

5. Physical Properties of Lipiodol 131I and Dosimetric Studies

   • Giannino Fava

   Pages 38-70

6. Clinical Results of Endolymphatic Radiotherapy

   • S. Chiappa, R. Musumeci, C. Uslenghi

   Pages 71-95

7. Side Effects and Complications

   • S. Chiappa, R. Musumeci, C. Uslenghi

   Pages 96-106

8. Results of Endolymphatic Radiotherapy: Histological Aspects

   • Federico Pizzetti, Umberto Veronesi

   Pages 107-118

9. Endolymphatic Radiotherapy in Relation to other Treatments for Malignant Lymphomas

   • S. Chiappa, R. Musumeci, C. Uslenghi

   Pages 119-123

10. Conclusions

    • S. Chiappa, R. Musumeci, C. Uslenghi

    Pages 124-125

11. Back Matter

    Pages 126-132

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Clinical trials with Lipiodol l3ll were started in 1961 by my associate, S. CHIAPPA, and a group of physicians at the Institute of Radiology and the National Cancer Institute in Milan and development has been vigorously pursued during the past years. Once the rationale of this method was established, various aspects of the prob­ lem have been investigated, particularly the distribution of the radioactive dye into the lymph nodes as weIl as its fate and dosimetry in the body tissues. This mono­ graph describes the extensive clinical evaluation and the radiological results obtained in a large group of patients with malignant lymphomas. Endolymphatic radiotherapy as a therapeutic tool employing radiönuclides has aroused interest at several meetings concerned with lymphology. In the re cent mono­ graph "Lymphography in cancer" by W. A. FUCHS, J. W. DAVIDSON and H. W. FISCHER, Dr. JANTET wrote a chapter on this specific subject. Many aspects are still debated, i. e. the choice of radionuclide, the specific clinical indications and the proper evaluation of the therapeutic effects. It is hoped that further studies will come to more precise conclusions.

• Lymphomas
• cancer
• clinical trial
• dosimetry
• lymphoma
• radiology
• radiotherapy
• therapy

• University of Milan, Italy

  Sergio Chiappa, Renato Musumeci, Carlo Uslenghi

• Radiological Department, Fatebenefratelli Hospital, Milan, Italy

  Sergio Chiappa

• National Cancer Institute, Milan, Italy

  Carlo Uslenghi

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