Acamprosate in Relapse Prevention of Alcoholism

1. Front Matter

   Pages I-XI

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2. Ethanol and the NMDA Receptor: Implications for Intoxication, Tolerance, Dependence, and Alcoholic Brain Damage

   • D. M. Lovinger

   Pages 1-26

3. The Neurobiology of Craving: Potential Mechanisms for Acamprosate

   • J. Littleton, M. al Qatari, H. Little

   Pages 27-46

4. Pharmacodynamics and Pharmacokinetics of Acamprosate: An Overview

   • P. Durbin, T. Hulot, S. Chabac

   Pages 47-64

5. Actions of Acamprosate on Neurons of the Central Nervous System

   • W. Zieglgänsberger, C. Hauser, C. Wetzel, J. Putzke, G. R. Siggins, R. Spanagel

   Pages 65-70

6. Acamprosate Decreases Alcohol Behavioral Dependence and Hypermotility After Alcohol Withdrawal But Increases Inhibitory Amino-Acids in Alcohol-Attracted Inbred Rats Using Microdialysis of the Nucleus Accumbens

   • P. De Witte, A. Dahchour, E. Quertemont, P. Durbin, S. Chabac

   Pages 71-91

7. Event-Related Potentials and EEG as Indicators of Central Neurophysiological Effects of Acamprosate

   • U. Hegerl, M. Soyka, J. Gallinat, S. Ufer, U. Preuß, R. Bottlender et al.

   Pages 93-104

8. Effects of Acamprosate on Verbal Learning in Healthy Young Subjects

   • N. Kathmann, M. Soyka, J. Gallinat, U. Hegerl

   Pages 105-110

9. Acamprosate in Clinical Practice: The French Experience

   • H.-J. Aubin

   Pages 111-119

10. Acamprosate Clinical Trials: Methodological Considerations for Assessment of Drinking Behaviour

    • A. S. Potgieter, P. Lehert

    Pages 121-132

11. Acamprosate in the Treatment of Alcohol Dependence: A 6-Month Postdetoxification Study

    • I. Pelc, O. Le Bon, P. Lehert, P. Verbanck

    Pages 133-142

12. Contribution of Acamprosate in Maintaining Abstinence in Weaned Alcohol-Dependent Patients: Additional Results of the Second French Multicentre Study

    • F. Paille, P. Parot, C. Gillet

    Pages 143-154

13. Clinical Efficacy of Acamprosate in the Treatment of Alcoholism

    • M. Soyka

    Pages 155-171

14. Back Matter

    Pages 173-175

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• Abhängigkeit
• Alkoholabhängigkeit
• Therapie
• alcohol
• alcohol-dependency
• alcoholism
• assessment
• clinical trial
• electroencephalography (EEG)
• nervous system
• neurobiology
• pharmacodynamics
• pharmacokinetics
• pharmacotherapy
• prevention

"I found much of value and interest in this book and have no hesitation in recommending it...It will certainly provide a comprehensive overview of excitatory amino acid receptors and theoretical models of craving" Addiction Biology

• Psychiatrische Klinik und Poliklinik, Universität München, München, Germany

  Michael Soyka

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