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Systemic Lupus Erythematosus

  • Book
  • © 1995

Overview

Editors:
  1. Peter A. Miescher

    1. Division d’Hématologie, Centre de Transfusion Sanguine, Hôpital Cantonal Universitaire, Geneva 4, Switzerland

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Table of contents (15 chapters)

  1. Front Matter

    Pages I-VI
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  2. Introduction

    • Peter A. Miescher
    Pages 1-2

  3. Mechanisms of genetic control of murine systemic lupus erythematosus

    • Shozo Izui, Ramón Merino, Masahiro Iwamoto, Liliane Fossati
    Pages 3-22

  4. The role of cytokines in the immunopathogenesis of lupus

    • Barry S. Handwerger, Violeta Rus, Ludmila da Silva, Charles S. Via
    Pages 23-50

  5. The cytokine network in the pathogenesis of systemic lupus erythematosus and possible therapeutic implications

    • David A. Horwitz, Chaim O. Jacob
    Pages 51-70

  6. Antibodies to CD45 and other cell membrane antigens in systemic lupus erythematosus

    • John B. Winfield, Philip Fernsten, Jan Czyzyk, Ena Wang, John Marchalonis
    Pages 71-80

  7. Antigenic specificities of “antiphospholipid” autoantibodies

    • Robert A. S. Roubey
    Pages 81-92

  8. Antiphospholipid antibodies and the antiphospholipid syndrome

    • E. Nigel Harris, Silvia S. Pierangeli
    Pages 93-115

  9. Lupus pregnancies and neonatal lupus

    • Michael D. Lockshin
    Pages 117-129

  10. Systemic lupus erythematosus in children

    • Alan M. Rosenberg
    Pages 131-149

  11. Systemic lupus erythematosus — disease management

    • Mark F. Gourley
    Pages 151-164

  12. Drug combination therapy of systemic lupus erythematosus

    • Peter A. Miescher, Hervé Favre, Robert Lemoine, You-Peng Huang
    Pages 165-181

  13. Central nervous system involvement in systemic lupus erythematosus: a new therapeutic approach with intrathecal dexamethasone and methotrexate

    • G. Valesini, R. Priori, A. Francia, G. Balestrieri, A. Tincani, P. Airo et al.
    Pages 183-191

  14. Extracorporeal photochemotherapy for the treatment of lupus erythematosus: preliminary observations

    • Robert M. Knobler
    Pages 193-195

  15. Immunological intervention reveals reciprocal roles for tumor necrosis factor-α and interleukin-10 in rheumatoid arthritis and systemic lupus erythematosus

    • Marc Feldmann
    Pages 197-206

  16. Prognosis in systemic lupus erythematosus

    • John M. Esdaile
    Pages 207-225
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Keywords

About this book

During the past 50 years, systemic lupus erythematosus (SLE) has been the main subject in the field of immunopathology. Each individual discovery was followed by the discovery of a multitude of related immune phenomena. This book reflects the present status of our understanding of this protean disease. Various animal models clearly show that different gene combinations can lead to the final clinical expression of SLE, with HLA class II genes probably responsible for the targeting of the autoimmune response. Similarly, research on cytokines in SLE patients has shown that SLE is a syndrome depending on different pathways. Finally, the question of prognosis is discussed. Fortunately, with every passing decade, the prognosis for patients with SLE gets better and better.

Editors and Affiliations

  • Division d’Hématologie, Centre de Transfusion Sanguine, Hôpital Cantonal Universitaire, Geneva 4, Switzerland

    Peter A. Miescher

Bibliographic Information

  • Book Title: Systemic Lupus Erythematosus

  • Editors: Peter A. Miescher

  • DOI: https://doi.org/10.1007/978-3-642-79622-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1995

  • Softcover ISBN: 978-3-642-79624-1Published: 27 December 2011

  • eBook ISBN: 978-3-642-79622-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VI, 225

  • Number of Illustrations: 2 b/w illustrations

  • Topics: Allergology, Immunology

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