Search for the Causes of Schizophrenia

1. Front Matter

   Pages I-XI

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2. Antecedents, Onset, and Early Course of Schizophrenia

   1. Front Matter

      Pages 1-1

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   2. Birth Cohort Study of the Antecedents of Psychosis: Ontogeny as Witness to Phylogenetic Origins

      • T. J. Crow, D. J. Done, A. Sacker

      Pages 3-20

   3. Antecedents of Schizophrenia: Moderating Effects of Development and Biological Sex

      • E. F. Walker, J. Weinstein, K. Baum, C. S. Neumann

      Pages 21-42

   4. Onset and Early Course of Schizophrenia

      • H. Häfner, K. Maurer, W. Löffler, S. Bustamante, W. van der Heiden, A. Riecher-Rössler et al.

      Pages 43-66

   5. Early Predictors of Onset and Course of Schizophrenia: Some Results from the Copenhagen High-Risk Study

      • J. Parnas, T. D. Cannon, S. A. Mednick, F. Schulsinger

      Pages 67-86

   6. Neurobehavioral Studies of Schizophrenic Children: A Developmental Perspective on Schizophrenic Disorders

      • R. F. Asarnow, R. Caplan, J. R. Asarnow

      Pages 87-113

   7. Antecedents, Onset, and Early Course of Schizophrenia: Discussion

      • L. E. DeLisi

      Pages 114-125

3. Schizophrenia: Disease or Syndrome?

   1. Front Matter

      Pages 127-127

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   2. Brain Imaging, Psychopathology and Neuropathology

      • E. C. Johnstone

      Pages 129-140

   3. Idiopathic and Organic Presentations of Schizophrenia

      • M. R. Trimble

      Pages 141-149

   4. Associations Between Regional Brain Abnormalities and Specific Syndromes in Schizophrenia

      • P. F. Liddle

      Pages 150-156

   5. Genetic Heterogeneity and Phenotype Variation of Schizophrenia

      • W. Maier

      Pages 157-185

   6. Schizophrenia: Disease or Syndrome? Discussion

      • R. M. Murray, P. Jones

      Pages 186-192

4. Brain, Receptors and Schizophrenia

   1. Front Matter

      Pages 193-193

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   2. Multiple Dopamine Receptors: Implications for Schizophrenia

      • P. Sokoloff, M.-P. Martres, D. Levesque, J. Diaz, C. Pilon, N. Griffon et al.

      Pages 195-214

   3. Increased Breakdown of Membrane Phospholipids in Schizophrenia: Implications for the Hypofrontality Hypothesis

      • W. F. Gattaz, J. Brunner, A. Schmitt, A. Maras

      Pages 215-226

   4. 31P Magnetic Resonance Spectroscopy Study of Brain Metabolism in Schizophrenia

      • R. McClure, M. Keshavan, N. J. Minshew, K. Panchalingam, J. W. Pettegrew

      Pages 227-251

   5. Positron Emission Tomography, Receptors, and Schizophrenia

      • F.-A. Wiesel

      Pages 252-262

   6. Brain, Receptors, and Schizophrenia: Discussion

      • F. A. Henn

      Pages 263-267

This volume presents the contributions to the third symposium on the "Search for the Causes of Schizophrenia". The first symposium was organized by the Central Institute of Mental Health on the occasion of the 600th anniversary of the University of Heidelberg in 1986. Its objective was to give an overview of the rapid development in schizophrenia research in a situation characterized by an excessive variety of methods and topics. It was our intention, through substantial contributions to topical areas of schizophrenia research and through intensive discussions, to further the exohange of hypotheses and results and thus open up ways towards new concepts integrating different methodological approaches or towards new models of explanation. The first symposium was a great success. The publication of the proceedings (Hafner et al. 1987) was received with enthusiasm and recommended in leading journals "as the best available state-of-the-art analysis of current research on the aetiology of schizophrenia". For this reason we held a second and a third symposium entitled "Search for the Causes of Schizophrenia" under the same auspices and at the same place in 1989 and 1993.

• PET
• Syndrom
• Verhaltensforschung
• biologische Psychiatrie
• brain
• brain imaging
• genetics
• neuropathology
• positron emission tomography (PET)
• psychiatry
• psychology
• psychopathology
• psychosis
• schizophrenia
• syndromes

• Central Institute of Mental Health, Mannheim, Germany

  Heinz Häfner, Wagner Farid Gattaz

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